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QuickView for Fzd6 (gene)


Gene Symbol:
FZD6 Homo sapiens Homo sapiens
Full name:
frizzled class receptor 6
Synonyms:
FZ-6, FZ6, HFZ6, NDNC10, frizzled-6, frizzled 6, seven transmembrane spanning receptor, frizzled family receptor 6, frizzled homolog 6, seven transmembrane helix receptor
Genomic Location:
Chr 8: 104380276-104414270
Description:
This gene represents a member of the 'frizzled' gene family, which encode 7-transmembrane domain proteins that are receptors for Wnt signaling proteins. The protein encoded by this family member contains a signal peptide, a cysteine-rich domain in the N-terminal extracellular region, and seven transmembrane domains, but unlike other family members,...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 8
8q22.3





GO Molecular Function

peptide binding | amyloid-beta binding | transmembrane signaling receptor activity | enzyme binding | ubiquitin-like protein ligase binding | amide binding | signaling receptor activity | protein binding | ubiquitin protein ligase binding | Wnt-activated receptor activity | Wnt-protein binding

GO Biological Process

brain development | limb development | molting cycle | inner ear morphogenesis | morphogenesis of an epithelium | negative regulation of cellular process | embryonic appendage morphogenesis | nervous system development | cellular process | epithelial tube morphogenesis | limb morphogenesis | negative regulation of signaling | canonical Wnt signaling pathway | hemostasis | regulation of canonical Wnt signaling pathway | tissue development | morphogenesis of a polarized epithelium | regulation of cellular process | regulation of metabolic process | epithelium development | regulation of establishment of planar polarity | head development | response to stimulus | nail development | embryonic limb morphogenesis | embryonic epithelial tube formation | response to stress | tube morphogenesis | epithelial tube formation | midbrain development | brain morphogenesis | G-protein coupled receptor signaling pathway | Wnt signaling pathway, planar cell polarity pathway | embryo development | cell-cell signaling | embryonic nail plate morphogenesis | cell surface receptor signaling pathway involved in cell-cell signaling | blood coagulation | regulation of nucleic acid-templated transcription | system development | regulation of signal transduction | Wnt signaling pathway | multicellular organism development | wound healing | regulation of gene expression | platelet activation | neural tube closure | animal organ morphogenesis | regulation of nitrogen compound metabolic process | negative regulation of DNA-binding transcription factor activity | neural tube formation | non-canonical Wnt signaling pathway | cell proliferation | neural tube development | epidermis development | skin development | sensory organ development | establishment of body hair planar orientation | chordate embryonic development | cell communication | regulation of cellular metabolic process | midbrain morphogenesis | inner ear development | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | establishment of planar polarity | coagulation | embryonic morphogenesis | embryonic organ morphogenesis | Wnt signaling pathway, calcium modulating pathway | hair cycle | tissue morphogenesis | response to wounding | regulation of animal organ morphogenesis | regulation of DNA-binding transcription factor activity | establishment of tissue polarity | anatomical structure development | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | regulation of body fluid levels | embryonic organ development | ear development | hair cycle process | morphogenesis of embryonic epithelium | animal organ development | skin epidermis development | regulation of Wnt signaling pathway | neural precursor cell proliferation | cell proliferation in midbrain | cell activation | anatomical structure formation involved in morphogenesis | regulation of cell communication | Wnt-activated receptor activity | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of transcription, DNA-templated | establishment of body hair or bristle planar orientation | embryonic digit morphogenesis | anatomical structure morphogenesis | regulation of developmental process | developmental process | negative regulation of canonical Wnt signaling pathway | tube development | tube closure | tube formation | central nervous system development | negative regulation of Wnt signaling pathway | ear morphogenesis | hair follicle development | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | apical plasma membrane | organelle membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | apical part of cell | plasma membrane | vesicle | integral component of plasma membrane | membrane-bounded organelle | apicolateral plasma membrane | organelle | vesicle membrane | cell periphery | intracellular vesicle | cell surface | intracellular | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane