QuickView for G4s (gene)

Gene Symbol:

ARSB Homo sapiens

Full name:

arylsulfatase B

Synonyms:

ASB, G4S, MPS6, arylsulfatase B, N-acetylgalactosamine-4-sulfatase

Genomic Location:

Chr 5: 78108788-78318113

Description:

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency ...

View Full Description

Arylsulfatase B encoded by this gene belongs to the sulfatase family. The arylsulfatase B homodimer hydrolyzes sulfate groups of N-Acetyl-D-galactosamine, chondriotin sulfate, and dermatan sulfate. The protein is targeted to the lysozyme. Mucopolysaccharidosis type VI is an autosomal recessive lysosomal storage disorder resulting from a deficiency of arylsulfatase B. Two alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Canis lupus familiaris ,  Pan troglodytes ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

ETS_Q4 ,  ATAGGAA_MIR202 ,  TGCGCANK_UNKNOWN ,  OCT1_03

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-495

Cytogenetic Map:

5q14.1

search → result