Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for G6PD (gene)


Gene Symbol:
G6PD Homo sapiens Homo sapiens
Full name:
glucose-6-phosphate dehydrogenase
Synonyms:
G6PD1, glucose-6-phosphate 1-dehydrogenase
Genomic Location:
Chr X: 153412800-153428981
Description:
This gene encodes glucose-6-phosphate dehydrogenase. This protein is a cytosolic enzyme encoded by a housekeeping X-linked gene whose main function is to produce NADPH, a key electron donor in the defense against oxidizing agents and in reductive biosynthetic reactions. G6PD is remarkable for its genetic diversity. Many variants of G6PD, mostly pro...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Bos taurus Canis lupus familiaris Danio rerio Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr X
Xq28





GO Molecular Function

oxidoreductase activity, acting on CH-OH group of donors | NADP binding | cofactor binding | nucleotide binding | coenzyme binding | monosaccharide binding | catalytic activity | glucose binding | identical protein binding | organic cyclic compound binding | carbohydrate binding | protein binding | protein homodimerization activity | protein dimerization activity | glucose-6-phosphate dehydrogenase activity | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | heterocyclic compound binding | oxidoreductase activity | small molecule binding

GO Biological Process

response to extracellular stimulus | brain development | regulation of muscle system process | response to nutrient levels | oxidoreductase activity, acting on CH-OH group of donors | regulation of cell development | regulation of localization | sulfur compound metabolic process | regulation of programmed cell death | regulation of cardiac muscle cell differentiation | erythrocyte homeostasis | glutathione metabolic process | myeloid cell differentiation | negative regulation of cellular process | response to metal ion | glucose metabolic process | regulation of heart growth | cell differentiation | negative regulation of organ growth | nervous system development | response to drug | erythrocyte maturation | response to antibiotic | regulation of neuron death | sterol metabolic process | cellular process | negative regulation of muscle organ development | cell maturation | nucleotide metabolic process | regulation of cell growth involved in cardiac muscle cell development | negative regulation of developmental growth | immune system development | ribose phosphate metabolic process | regulation of striated muscle tissue development | myeloid cell development | response to inorganic substance | negative regulation of cellular metabolic process | regulation of cell differentiation | regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | negative regulation of muscle hypertrophy | regulation of cellular process | negative regulation of cardiocyte differentiation | regulation of apoptotic process | regulation of metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | steroid biosynthetic process | head development | negative regulation of cardiac muscle tissue development | response to stimulus | pentose-phosphate shunt | negative regulation of striated muscle cell differentiation | response to stress | positive regulation of cation transmembrane transport | alcohol metabolic process | response to alcohol | midbrain development | cellular nitrogen compound metabolic process | pentose biosynthetic process | negative regulation of muscle tissue development | carbohydrate derivative biosynthetic process | negative regulation of metabolic process | cofactor metabolic process | hemopoiesis | response to iron ion | myeloid cell homeostasis | response to ethanol | organic hydroxy compound metabolic process | system development | nitrogen compound metabolic process | negative regulation of growth | positive regulation of calcium ion transmembrane transport | multicellular organism development | phosphorus metabolic process | lipid metabolic process | cellular response to oxidative stress | cellular response to stress | negative regulation of cardiac muscle cell differentiation | organophosphate metabolic process | sterol biosynthetic process | negative regulation of cardiac muscle hypertrophy | positive regulation of ion transmembrane transport | regulation of nitrogen compound metabolic process | monosaccharide metabolic process | small molecule metabolic process | cellular amide metabolic process | substantia nigra development | response to oxidative stress | nucleobase-containing small molecule metabolic process | homeostasis of number of cells | carbohydrate biosynthetic process | biosynthetic process | cholesterol biosynthetic process | regulation of cellular protein metabolic process | lipid biosynthetic process | carbohydrate metabolic process | regulation of calcium ion transmembrane transport | negative regulation of protein glutathionylation | response to toxic substance | erythrocyte development | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of neuron apoptotic process | glyceraldehyde-3-phosphate metabolic process | regulation of protein metabolic process | negative regulation of striated muscle tissue development | homeostatic process | peptide metabolic process | pentose-phosphate shunt, oxidative branch | positive regulation of transport | negative regulation of cell growth | cellular aldehyde metabolic process | regulation of cardiac muscle hypertrophy | regulation of growth | response to organic substance | regulation of cardiac muscle tissue development | positive regulation of calcium ion transmembrane transport via high voltage-gated calcium channel | anatomical structure development | metabolic process | hexose metabolic process | developmental maturation | cholesterol metabolic process | oxidation-reduction process | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | positive regulation of ion transport | negative regulation of cellular protein metabolic process | glucose 6-phosphate metabolic process | NADPH regeneration | regulation of striated muscle cell differentiation | regulation of ion transmembrane transport | response to iron(III) ion | negative regulation of protein metabolic process | steroid metabolic process | negative regulation of cell growth involved in cardiac muscle cell development | glucose-6-phosphate dehydrogenase activity | response to organic cyclic compound | ribose phosphate biosynthetic process | cell development | regulation of developmental growth | NADP metabolic process | oxidoreductase activity, acting on the CH-OH group of donors, NAD or NADP as acceptor | regulation of organ growth | regulation of developmental process | regulation of ion transport | developmental process | regulation of muscle cell differentiation | erythrocyte differentiation | nicotinamide nucleotide metabolic process | regulation of cell growth | regulation of calcium ion transport | carbohydrate derivative metabolic process | regulation of transport | regulation of reactive oxygen species metabolic process | cellular modified amino acid metabolic process | heterocycle metabolic process | central nervous system development | negative regulation of muscle cell differentiation | pentose metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of cell death | oxidoreductase activity | response to food | negative regulation of cell development | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of calcium ion transport | negative regulation of reactive oxygen species metabolic process | neural nucleus development | regulation of muscle organ development | multicellular organismal process

GO Cellular Component

cytoplasmic side of plasma membrane | intracellular membrane-bounded organelle | cell | cytoplasmic side of membrane | cytoplasm | intracellular organelle | plasma membrane | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | extracellular space | cell periphery | cytosol | intracellular | membrane