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QuickView for GABRA2 (gene)


Gene Symbol:
GABRA2 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid type A receptor alpha2 subunit
Synonyms:
gamma-aminobutyric acid receptor subunit alpha-2, GABA(A) receptor subunit alpha-2
Genomic Location:
Chr 4: 45946463-46086702
Description:
GABA is the major inhibitory neurotransmitter in the mammalian brain where it acts at GABA-A receptors, which are ligand-gated chloride channels. Chloride conductance of these channels can be modulated by agents such as benzodiazepines that bind to the GABA-A receptor. At least 16 distinct subunits of GABA-A receptors have been identified. Alternat...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris Danio rerio Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4p12





GO Molecular Function

transmitter-gated ion channel activity | neurotransmitter receptor activity | anion transmembrane transporter activity | benzodiazepine receptor activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | inorganic anion transmembrane transporter activity | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | GABA receptor activity | anion channel activity | channel activity | inhibitory extracellular ligand-gated ion channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | establishment of localization | anion transmembrane transporter activity | cellular process | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | chemical synaptic transmission | anion transport | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | chloride transmembrane transport | response to stimulus | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | regulation of neurotransmitter levels | chloride transmembrane transporter activity | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | cell communication | anion transmembrane transport | cell surface receptor signaling pathway | anion channel activity | transmembrane transport | signaling | channel activity | synaptic transmission, GABAergic | inhibitory extracellular ligand-gated ion channel activity | neurotransmitter transport | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of organelle membrane | exocytic vesicle | integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | organelle membrane | cell projection membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | synaptic membrane | transport vesicle membrane | cytoplasm | intracellular organelle | receptor complex | dendritic tree | leading edge membrane | presynapse | protein-containing complex | cell projection | secretory vesicle | postsynaptic membrane | endomembrane system | postsynapse | plasma membrane | GABA receptor complex | cell leading edge | exocytic vesicle membrane | chloride channel complex | vesicle | transport vesicle | integral component of plasma membrane | synaptic vesicle | dendrite membrane | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | transmembrane transporter complex | ion channel complex | synaptic vesicle membrane | intracellular vesicle | integral component of synaptic vesicle membrane | intracellular | cell junction | membrane | cytoplasmic vesicle membrane | neuron projection membrane | GABA-A receptor complex | intrinsic component of plasma membrane