QuickView for GABRB2 (gene)

Gene Symbol:

GABRB2 Homo sapiens

Full name:

gamma-aminobutyric acid type A receptor beta2 subunit

Synonyms:

gamma-aminobutyric acid receptor subunit beta-2, GABA(A) receptor subunit beta-2, gamma-aminobutyric acid A receptor beta 2

Genomic Location:

Chr 5: 160648014-160907708

Description:

The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Al...

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The gamma-aminobutyric acid (GABA) A receptor is a multisubunit chloride channel that mediates the fastest inhibitory synaptic transmission in the central nervous system. This gene encodes GABA A receptor, beta 2 subunit. It is mapped to chromosome 5q34 in a cluster comprised of genes encoding alpha 1 and gamma 2 subunits of the GABA A receptor. Alternative splicing of this gene generates 2 transcript variants, differing by a 114 bp insertion.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

AACWWCAANK_UNKNOWN ,  TFIIA_Q6 ,  GCAAGGA_MIR502 ,  RSRFC4_Q2 ,  CTTTGA_LEF1_Q2 ,  CTAWWWATA_RSRFC4_Q2 ,  TCF4_Q5 ,  MEF2_02 ,  TATAAA_TATA_01 ,  CEBPDELTA_Q6 ,  LEF1_Q6 ,  PAX4_02 ,  CATTTCA_MIR203 ,  WYAAANNRNNNGCG_UNKNOWN ,  TGCGCANK_UNKNOWN ,  NKX61_01 ,  NRF1_Q6 ,  MEF2_03 ,  RORA2_01 ,  CTTTGT_LEF1_Q2 ,  TBP_01 ,  RCGCANGCGY_NRF1_Q6 ,  ACAWYAAAG_UNKNOWN

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-203

Cytogenetic Map:

5q34

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