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QuickView for GABRG1 (gene)


Gene Symbol:
GABRG1 Homo sapiens Homo sapiens
Full name:
gamma-aminobutyric acid type A receptor gamma1 subunit
Synonyms:
gamma-aminobutyric acid receptor subunit gamma-1, GABA(A) receptor subunit gamma-1, GABA(A) receptor, gamma, gamma-1 polypeptide, gamma-aminobutyric acid (GABA) A receptor, gamma 1
Genomic Location:
Chr 4: 45732543-45820839
Description:
The protein encoded by this gene belongs to the ligand-gated ionic channel family. It is an integral membrane protein and plays an important role in inhibiting neurotransmission by binding to the benzodiazepine receptor and opening an integral chloride channel. This gene is clustered with three other family members on chromosome 4.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
Cytogenetic Map:
chr 4
4p12


Transcripts Names
NM_173536
XM_017007990
Protein Names
Q8N1C3
Q5H9T8



GO Molecular Function

transmitter-gated ion channel activity | neurotransmitter receptor activity | anion transmembrane transporter activity | GABA receptor binding | benzodiazepine receptor activity | GABA-A receptor activity | passive transmembrane transporter activity | transmembrane signaling receptor activity | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | signaling receptor binding | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | inorganic anion transmembrane transporter activity | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | chloride transmembrane transporter activity | signaling receptor activity | transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | GABA receptor activity | protein binding | anion channel activity | channel activity | inhibitory extracellular ligand-gated ion channel activity | ion channel activity | substrate-specific channel activity

GO Biological Process

transmitter-gated ion channel activity | establishment of localization | anion transmembrane transporter activity | cellular process | gamma-aminobutyric acid signaling pathway | localization | passive transmembrane transporter activity | chemical synaptic transmission | anion transport | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | chloride transmembrane transport | response to stimulus | ion gated channel activity | neurotransmitter receptor activity involved in regulation of postsynaptic membrane potential | chloride channel activity | chloride transport | inorganic anion transport | G-protein coupled receptor signaling pathway | inorganic anion transmembrane transporter activity | cell-cell signaling | cell surface receptor signaling pathway involved in cell-cell signaling | GABA-gated chloride ion channel activity | transmitter-gated ion channel activity involved in regulation of postsynaptic membrane potential | regulation of membrane potential | chloride transmembrane transporter activity | ion transmembrane transport | regulation of postsynaptic membrane potential | nervous system process | synaptic signaling | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | cell communication | anion transmembrane transport | cell surface receptor signaling pathway | anion channel activity | transmembrane transport | signaling | channel activity | synaptic transmission, GABAergic | inhibitory extracellular ligand-gated ion channel activity | ion channel activity | ion transport | substrate-specific channel activity | signal transduction | multicellular organismal process

GO Cellular Component

integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cell projection membrane | cell | intrinsic component of membrane | synaptic membrane | receptor complex | dendritic tree | leading edge membrane | protein-containing complex | cell projection | postsynaptic membrane | postsynapse | plasma membrane | GABA receptor complex | cell leading edge | chloride channel complex | integral component of plasma membrane | dendrite membrane | cell periphery | transmembrane transporter complex | ion channel complex | cell junction | membrane | neuron projection membrane | GABA-A receptor complex | intrinsic component of plasma membrane