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QuickView for GALR1 (gene)


Gene Symbol:
GALR1 Homo sapiens Homo sapiens
Full name:
galanin receptor 1
Synonyms:
GALNR, GALNR1, galanin receptor type 1, GAL1-R, GALR-1
Genomic Location:
Chr 18: 73090721-73111081
Description:
The neuropeptide galanin elicits a range of biological effects by interaction with specific G-protein-coupled receptors. Galanin receptors are seven-transmembrane proteins shown to activate a variety of intracellular second-messenger pathways. GALR1 inhibits adenylyl cyclase via a G protein of the Gi/Go family. GALR1 is widely expressed in the b...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 18
18q23


Transcripts Names
NM_001480
XM_017025691
Protein Names
P47211
Q4VBL7



GO Molecular Function

peptide binding | galanin receptor activity | peptide hormone binding | transmembrane signaling receptor activity | neuropeptide binding | G-protein coupled receptor activity | neuropeptide receptor activity | amide binding | signaling receptor activity | hormone binding | protein binding | peptide receptor activity | G-protein coupled peptide receptor activity

GO Biological Process

positive regulation of macromolecule biosynthetic process | intracellular signal transduction | regulation of localization | galanin receptor activity | cellular chemical homeostasis | regulation of lipid transport | positive regulation of cellular biosynthetic process | cellular process | neuropeptide signaling pathway | cellular homeostasis | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | regulation of cytosolic calcium ion concentration | calcium ion homeostasis | G-protein coupled receptor activity | negative regulation of lyase activity | response to stimulus | regulation of response to drug | neuropeptide receptor activity | positive regulation of hormone secretion | G-protein coupled receptor signaling pathway | positive regulation of RNA biosynthetic process | metal ion homeostasis | regulation of nucleic acid-templated transcription | negative regulation of catalytic activity | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of catalytic activity | regulation of hormone levels | regulation of hormone secretion | regulation of gene expression | positive regulation of secretion | positive regulation of cellular metabolic process | cellular ion homeostasis | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | second-messenger-mediated signaling | negative regulation of adenylate cyclase activity | positive regulation of lipid localization | regulation of cyclase activity | cation homeostasis | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of response to drug | cyclic-nucleotide-mediated signaling | regulation of endocrine process | cellular calcium ion homeostasis | homeostatic process | regulation of RNA metabolic process | positive regulation of transport | cAMP-mediated signaling | regulation of RNA biosynthetic process | chemical homeostasis | regulation of secretion | ion homeostasis | regulation of adenylate cyclase activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | signaling | G-protein coupled peptide receptor activity | regulation of transcription, DNA-templated | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | positive regulation of lipid transport | positive regulation of cortisol secretion | divalent inorganic cation homeostasis | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression

GO Cellular Component

integral component of membrane | cell | intrinsic component of membrane | plasma membrane | integral component of plasma membrane | cell periphery | intracellular | membrane | intrinsic component of plasma membrane