QuickView for GATA1 (gene)

Gene Symbol:

GATA1 Homo sapiens

Full name:

GATA binding protein 1

Synonyms:

ERYF1, GATA-1, GF-1, GF1, NF-E1, NFE1, XLANP, XLTDA, XLTT, erythroid transcription factor, GATA-binding factor 1, NF-E1 DNA-binding protein, erythroid transcription factor 1, globin transcription factor 1, nuclear factor, erythroid 1, transcription factor GATA1

Genomic Location:

Chr X: 48529906-48537662

Description:

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

This gene encodes a protein which belongs to the GATA family of transcription factors. The protein plays an important role in erythroid development by regulating the switch of fetal hemoglobin to adult hemoglobin. Mutations in this gene have been associated with X-linked dyserythropoietic anemia and thrombocytopenia.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Canis lupus familiaris ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATA1_03 ,  GATA_Q6 ,  GATA_C ,  E2F4DP1_01 ,  GCANCTGNY_MYOD_Q6 ,  ARP1_01 ,  GATAAGR_GATA_C ,  GATA1_04 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTA_AREB6_01 ,  E2F1_Q6_01 ,  AP4_01 ,  E2F1DP2_01 ,  LMO2COM_02 ,  GATA6_01 ,  E2F1DP1_01 ,  AP2REP_01 ,  GATA1_05 ,  E2F_02 ,  SREBP_Q3 ,  PAX_Q6 ,  GTGGGTGK_UNKNOWN ,  E2F4DP2_01 ,  CAGCTG_AP4_Q5 ,  SMAD_Q6 ,  P300_01 ,  AACTTT_UNKNOWN ,  CP2_01 ,  GGGTGGRR_PAX4_03 ,  TAXCREB_01 ,  E2F1_Q6 ,  SGCGSSAAA_E2F1DP2_01 ,  OLF1_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-140

Cytogenetic Map:

Xp11.23

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