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QuickView for GGH (gene)


Gene Symbol:
GGH Homo sapiens Homo sapiens
Full name:
gamma-glutamyl hydrolase
Synonyms:
GH, gamma-glutamyl hydrolase, gamma-Glu-X carboxypeptidase, gamma-glutamyl hydrolase (conjugase, folylpolygammaglutamyl hydrolase)
Genomic Location:
Chr 8: 64090192-64113940
Description:
This gene catalyzes the hydrolysis of folylpoly-gamma-glutamates and antifolylpoly-gamma-glutamates by the removal of gamma-linked polyglutamates and glutamate.
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Danio rerio Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 8
8q12.3


Transcripts Names
NM_003878
XM_011517623
Protein Names
Q92820



GO Molecular Function

gamma-glutamyl-peptidase activity | hydrolase activity | catalytic activity | exopeptidase activity | omega peptidase activity | peptidase activity

GO Biological Process

exocytosis | neutrophil activation | proteolysis | establishment of localization | response to hormone | gamma-glutamyl-peptidase activity | response to metal ion | response to drug | response to antibiotic | cellular process | secretion | leukocyte degranulation | localization | response to inorganic substance | response to peptide hormone | leukocyte activation | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | folic acid-containing compound metabolic process | response to stimulus | neutrophil degranulation | leukocyte activation involved in immune response | response to peptide | secretion by cell | response to alcohol | cellular nitrogen compound metabolic process | cofactor metabolic process | pteridine-containing compound metabolic process | response to ethanol | response to nitrogen compound | nitrogen compound metabolic process | leukocyte mediated immunity | exopeptidase activity | small molecule metabolic process | cellular amide metabolic process | vesicle-mediated transport | regulated exocytosis | response to toxic substance | cell activation involved in immune response | myeloid cell activation involved in immune response | neutrophil activation involved in immune response | response to zinc ion | carboxylic acid metabolic process | protein metabolic process | response to organic substance | response to insulin | metabolic process | immune response | organic substance metabolic process | cell activation | organic acid metabolic process | omega peptidase activity | tetrahydrofolylpolyglutamate metabolic process | neutrophil mediated immunity | response to organonitrogen compound | cellular modified amino acid metabolic process | heterocycle metabolic process | immune system process | cellular metabolic process | peptidase activity | macromolecule metabolic process

GO Cellular Component

secretory granule | azurophil granule lumen | intracellular membrane-bounded organelle | tertiary granule | cytoplasmic vesicle | cell | vacuolar lumen | cytoplasmic vesicle lumen | cytoplasm | intracellular organelle | melanosome | secretory vesicle | endomembrane system | vacuole | vesicle | extracellular exosome | specific granule | lytic vacuole | extracellular region | membrane-bounded organelle | extracellular vesicle | specific granule lumen | nucleus | organelle | lysosome | extracellular space | tertiary granule lumen | membrane-enclosed lumen | azurophil granule | secretory granule lumen | cytosol | intracellular vesicle | intracellular | vesicle lumen