QuickView for GLUD2 (gene)
- Gene Symbol:
- GLUD2
Homo sapiens - Full name:
- glutamate dehydrogenase 2
- Synonyms:
- GDH2, GLUDP1, glutamate dehydrogenase 2, mitochondrial, GDH 2, glutamate dehydrogenase pseudogene 1, testicular secretory protein Li 14
- Genomic Location:
- Chr X: 120009143-120011477
- Description:
-
The protein encoded by this gene is localized to the mitochondrion and acts as a homohexamer to recycle glutamate during neurotransmission. The encoded enzyme catalyzes the reversible oxidative deamination of glutamate to alpha-ketoglutarate. This gene is intronless.
- Orthologs:
- Mus musculus , Macaca mulatta , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
Xq24
GO Molecular Function
ADP binding | oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | guanyl ribonucleotide binding | ribonucleoside binding | leucine binding | cation binding | carboxylic acid binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | glutamate dehydrogenase (NAD+) activity | catalytic activity | anion binding | adenyl nucleotide binding | amino acid binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | glutamate dehydrogenase [NAD(P)+] activity | purine ribonucleoside triphosphate binding | GTP binding | oxidoreductase activity, acting on the CH-NH2 group of donors | nucleoside binding | purine ribonucleotide binding | adenyl ribonucleotide binding | organic acid binding | heterocyclic compound binding | oxidoreductase activity | guanyl nucleotide binding | small molecule binding
GO Biological Process
oxidoreductase activity, acting on the CH-NH2 group of donors, NAD or NADP as acceptor | cellular amino acid catabolic process | cellular process | organic substance catabolic process | dicarboxylic acid metabolic process | cellular amino acid metabolic process | catabolic process | glutamate biosynthetic process | dicarboxylic acid catabolic process | carboxylic acid catabolic process | cellular amino acid biosynthetic process | glutamate dehydrogenase (NAD+) activity | cellular biosynthetic process | nitrogen compound metabolic process | glutamate metabolic process | small molecule metabolic process | biosynthetic process | glutamate catabolic process | glutamate dehydrogenase [NAD(P)+] activity | carboxylic acid metabolic process | metabolic process | oxidation-reduction process | organic substance metabolic process | oxidoreductase activity, acting on the CH-NH2 group of donors | organonitrogen compound catabolic process | organic acid metabolic process | cellular metabolic process | oxidoreductase activity
GO Cellular Component
intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | mitochondrion | membrane-bounded organelle | organelle | intracellular
