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QuickView for GOPC (gene)


Gene Symbol:
GOPC Homo sapiens Homo sapiens
Full name:
golgi associated PDZ and coiled-coil motif containing
Synonyms:
CAL, FIG, GOPC1, PIST, dJ94G16.2, Golgi-associated PDZ and coiled-coil motif-containing protein, CFTR-associated ligand, PDZ protein interacting specifically with TC10, PDZ/coiled-coil domain binding partner for the rho-family GTPase TC10, dJ94G16.2 PIST, fused in glioblastoma, golgi-associated PDZ and coiled-coil motif containing protein
Genomic Location:
Chr 6: 117988125-118030374
Description:
This gene encodes a Golgi protein with a PDZ domain. The PDZ domain is globular and proteins which contain them bind other proteins through short motifs near the C-termini. Mice which are deficient in the orthologous protein have globozoospermia and are infertile. Multiple transcript variants encoding different isoforms have been found for this gen...
Orthologs:
Mus musculus Rattus norvegicus C. elegans Macaca mulatta Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 6
6q22.1


Transcripts Names
NM_001017408
NM_020399
XM_024446496
Protein Names
Q9HD26
A6NM30
Q969U8
Q59FS4



GO Molecular Function

signaling receptor binding | GTPase regulator activity | molecular function regulator | ion channel binding | frizzled binding | identical protein binding | protein binding | protein homodimerization activity | protein dimerization activity | G-protein coupled receptor binding | enzyme regulator activity | protein C-terminus binding

GO Biological Process

protein homooligomerization | nucleus organization | developmental process involved in reproduction | regulation of cellular localization | regulation of localization | establishment of localization | negative regulation of cellular process | regulation of protein localization to membrane | cell differentiation | male gamete generation | intracellular transport | cellular process | localization | protein transport | negative regulation of protein localization to plasma membrane | multicellular organismal reproductive process | macromolecule localization | establishment of localization in cell | negative regulation of establishment of protein localization | gamete generation | Golgi to plasma membrane transport | regulation of cellular process | regulation of Golgi to plasma membrane protein transport | cellular component organization | negative regulation of protein transport | regulation of cellular protein localization | GTPase regulator activity | germ cell development | negative regulation of transporter activity | reproduction | cellular localization | negative regulation of transport | regulation of protein transport | spermatid differentiation | cellular component assembly | regulation of peptide transport | negative regulation of transmembrane transport | molecular function regulator | reproductive process | protein complex oligomerization | regulation of catalytic activity | regulation of protein localization to cell surface | negative regulation of cellular protein localization | post-Golgi vesicle-mediated transport | organic substance transport | spermatid nucleus differentiation | regulation of anion channel activity | peptide transport | cytoplasmic sequestering of protein | vesicle-mediated transport | negative regulation of ion transmembrane transport | negative regulation of ion transport | maintenance of protein location | negative regulation of Golgi to plasma membrane protein transport | apical protein localization | Golgi vesicle transport | negative regulation of anion channel activity | multicellular organism reproduction | protein-containing complex assembly | regulation of establishment of protein localization | anatomical structure development | regulation of protein localization to plasma membrane | amide transport | regulation of vesicle-mediated transport | cytoplasmic sequestering of CFTR protein | negative regulation of ion transmembrane transporter activity | spermatid development | regulation of ion transmembrane transport | establishment of protein localization | negative regulation of molecular function | ER to Golgi vesicle-mediated transport | cell development | regulation of transmembrane transporter activity | protein localization | regulation of ion transmembrane transporter activity | enzyme regulator activity | regulation of ion transport | developmental process | organelle organization | spermatogenesis | negative regulation of protein localization to cell surface | regulation of transport | regulation of anion transport | regulation of protein localization | sexual reproduction | multicellular organismal process

GO Cellular Component

dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | organelle membrane | clathrin-coated vesicle | cytoplasmic vesicle | Golgi-associated vesicle membrane | cell | synaptic membrane | cytoplasm | intracellular organelle | dendritic tree | Golgi apparatus | protein-containing complex | cell projection | postsynaptic membrane | endomembrane system | postsynapse | plasma membrane | Golgi-associated vesicle | vacuole | vesicle | transport vesicle | postsynaptic density | asymmetric synapse | lytic vacuole | Golgi membrane | membrane-bounded organelle | organelle | postsynaptic specialization | lysosome | cell periphery | trans-Golgi network transport vesicle | intracellular vesicle | intracellular | cell junction | lysosomal membrane | membrane | vacuolar membrane | coated vesicle