QuickView for GOT1 (gene)

Gene Symbol:

GOT1 Homo sapiens

Full name:

glutamic-oxaloacetic transaminase 1

Synonyms:

AST1, ASTQTL1, GIG18, cAspAT, cCAT, aspartate aminotransferase, cytoplasmic, aspartate aminotransferase 1, aspartate transaminase 1, cysteine aminotransferase, cytoplasmic, cysteine transaminase, cytoplasmic, glutamate oxaloacetate transaminase 1, glutamic-oxaloacetic transaminase 1, soluble, growth-inhibiting protein 18, testis secretory sperm-binding protein Li 196a, transaminase A

Genomic Location:

Chr 10: 101146618-101180336

Description:

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

Glutamic-oxaloacetic transaminase is a pyridoxal phosphate-dependent enzyme which exists in cytoplasmic and mitochondrial forms, GOT1 and GOT2, respectively. GOT plays a role in amino acid metabolism and the urea and tricarboxylic acid cycles. The two enzymes are homodimeric and show close homology.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Danio rerio ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GATTGGY_NFY_Q6_01 ,  TGGNNNNNNKCCAR_UNKNOWN ,  TGACCTY_ERR1_Q2 ,  GGGAGGRR_MAZ_Q6 ,  RREB1_01 ,  NF1_Q6 ,  ACCAAAG_MIR9 ,  CEBPB_02 ,  TGCCAAR_NF1_Q6 ,  CEBP_C ,  ERR1_Q2

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-9

Cytogenetic Map:

10q24.2

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