QuickView for GPRC5A (gene)
- Gene Symbol:
- GPRC5A
Homo sapiens - Full name:
- G protein-coupled receptor class C group 5 member A
- Synonyms:
- GPCR5A, PEIG-1, RAI3, RAIG1, TIG1, retinoic acid-induced protein 3, G-protein coupled receptor family C group 5 member A, TPA induced gene 1, orphan G-protein-coupling receptor PEIG-1, phorbol ester induced gene 1, phorbol ester induced protein-1, retinoic acid induced 3, retinoic acid responsive, retinoic acid-induced gene 1 protein
- Genomic Location:
- Chr 12: 12935223-12957867
- Description:
-
This gene encodes a member of the type 3 G protein-coupling receptor family, characterized by the signature 7-transmembrane domain motif. The encoded protein may be involved in interaction between retinoid acid and G protein signalling pathways. Retinoic acid plays a critical role in development, cellular growth, and differentiation. This gene may ...
- Orthologs:
- Mus musculus , Rattus norvegicus , Macaca mulatta , Gallus gallus , Pan troglodytes , Canis lupus familiaris , Bos taurus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
12p13.1
GO Molecular Function
protein kinase activator activity | enzyme activator activity | protein kinase regulator activity | cadherin binding | kinase regulator activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | molecular function regulator | signaling receptor activity | cell adhesion molecule binding | protein binding | kinase activator activity | enzyme regulator activity
GO Biological Process
negative regulation of signaling receptor activity | negative regulation of phosphorylation | protein kinase activator activity | enzyme activator activity | protein kinase regulator activity | negative regulation of cellular process | negative regulation of kinase activity | negative regulation of protein phosphorylation | positive regulation of phosphate metabolic process | cellular process | negative regulation of signaling | kinase regulator activity | positive regulation of protein kinase activity | positive regulation of catalytic activity | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | positive regulation of cellular protein metabolic process | negative regulation of epidermal growth factor receptor signaling pathway | G-protein coupled receptor activity | response to stimulus | regulation of peptidyl-tyrosine phosphorylation | positive regulation of protein metabolic process | negative regulation of protein kinase activity | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | activation of protein kinase activity | molecular function regulator | regulation of protein tyrosine kinase activity | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of catalytic activity | regulation of phosphorylation | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of nitrogen compound metabolic process | regulation of cellular protein metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | positive regulation of molecular function | regulation of signaling receptor activity | regulation of epidermal growth factor-activated receptor activity | positive regulation of protein modification process | regulation of kinase activity | kinase activator activity | negative regulation of ERBB signaling pathway | regulation of epidermal growth factor receptor signaling pathway | negative regulation of cellular protein metabolic process | positive regulation of kinase activity | regulation of phosphate metabolic process | negative regulation of protein metabolic process | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | regulation of ERBB signaling pathway | negative regulation of peptidyl-tyrosine phosphorylation | positive regulation of phosphorylation | enzyme regulator activity | negative regulation of epidermal growth factor-activated receptor activity | positive regulation of metabolic process | negative regulation of protein tyrosine kinase activity | signal transduction | regulation of signaling | regulation of phosphorus metabolic process
GO Cellular Component
integral component of membrane | intracellular membrane-bounded organelle | organelle membrane | cytoplasmic vesicle | cell | nuclear lumen | intrinsic component of membrane | nucleolus | cytoplasm | intracellular organelle | receptor complex | protein-containing complex | plasma membrane | vesicle | extracellular exosome | integral component of plasma membrane | extracellular region | membrane-bounded organelle | extracellular vesicle | nucleus | organelle | vesicle membrane | extracellular space | cell periphery | membrane-enclosed lumen | intracellular vesicle | intracellular | membrane | cytoplasmic vesicle membrane | intrinsic component of plasma membrane
