QuickView for GPS1 (gene)
- Gene Symbol:
- GPS1
Homo sapiens - Full name:
- G protein pathway suppressor 1
- Synonyms:
- COPS1, CSN1, SGN1, COP9 signalosome complex subunit 1, JAB1-containing signalosome subunit 1
- Genomic Location:
- Chr 17: 77603052-77608635
- Description:
-
This gene is known to suppress G-protein and mitogen-activated signal transduction in mammalian cells. The encoded protein shares significant similarity with Arabidopsis FUS6, which is a regulator of light-mediated signal transduction in plant cells.
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Gallus gallus , Canis lupus familiaris , Bos taurus , Pan troglodytes , Danio rerio
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
17q25.3
GO Molecular Function
enzyme inhibitor activity | GTPase regulator activity | molecular function regulator | protein binding | enzyme regulator activity | GTPase inhibitor activity
GO Biological Process
protein modification by small protein removal | negative regulation of phosphorylation | negative regulation of MAPK cascade | nucleotide-excision repair, DNA damage recognition | intracellular signal transduction | proteolysis | negative regulation of cellular process | negative regulation of kinase activity | regulation of MAP kinase activity | negative regulation of protein phosphorylation | cellular process | negative regulation of signaling | negative regulation of cellular metabolic process | regulation of cellular process | regulation of metabolic process | inactivation of MAPK activity | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | cellular component organization | MAPK cascade | protein deneddylation | response to stimulus | enzyme inhibitor activity | JNK cascade | signal transduction by protein phosphorylation | GTPase regulator activity | response to stress | negative regulation of protein kinase activity | cellular nitrogen compound metabolic process | negative regulation of metabolic process | protein modification process | macromolecule modification | molecular function regulator | stress-activated protein kinase signaling cascade | DNA repair | nitrogen compound metabolic process | regulation of signal transduction | negative regulation of phosphate metabolic process | negative regulation of catalytic activity | regulation of MAPK cascade | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | cellular response to stress | regulation of nitrogen compound metabolic process | negative regulation of protein serine/threonine kinase activity | stress-activated MAPK cascade | regulation of cellular protein metabolic process | phosphorylation | regulation of GTPase activity | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | negative regulation of MAP kinase activity | protein metabolic process | regulation of kinase activity | DNA metabolic process | regulation of intracellular signal transduction | negative regulation of intracellular signal transduction | metabolic process | nucleotide-excision repair | nucleobase-containing compound metabolic process | organic substance metabolic process | negative regulation of cellular protein metabolic process | protein modification by small protein conjugation or removal | regulation of phosphate metabolic process | negative regulation of protein metabolic process | transcription-coupled nucleotide-excision repair | regulation of cell communication | negative regulation of molecular function | negative regulation of signal transduction | signaling | cellular protein metabolic process | enzyme regulator activity | organelle organization | cellular protein modification process | negative regulation of GTPase activity | heterocycle metabolic process | negative regulation of hydrolase activity | chromosome organization | cellular metabolic process | GTPase inhibitor activity | signal transduction | regulation of signaling | post-translational protein modification | macromolecule metabolic process | regulation of phosphorus metabolic process
GO Cellular Component
intracellular membrane-bounded organelle | COP9 signalosome | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | membrane-bounded organelle | nucleus | organelle | membrane-enclosed lumen | cytosol | intracellular
