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QuickView for GRIN3B (gene)


Gene Symbol:
GRIN3B Homo sapiens Homo sapiens
Full name:
glutamate ionotropic receptor NMDA type subunit 3B
Synonyms:
GluN3B, NR3B, glutamate receptor ionotropic, NMDA 3B, N-methyl-D-aspartate receptor subtype 3B, NMDA receptor subunit 3B, NMDA type glutamate receptor subunit NR3B, NMDAR3B, glutamate [NMDA] receptor subunit 3B, glutamate receptor, ionotropic, N-methyl-D-aspartate 3B
Genomic Location:
Chr 19: 951437-960723
Description:
The protein encoded by this gene is a subunit of an N-methyl-D-aspartate (NMDA) receptor. The encoded protein is found primarily in motor neurons, where it forms a heterotetramer with GRIN1 to create an excitatory glycine receptor. Variations in this gene have been proposed to be linked to schizophrenia.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Danio rerio Bos taurus
External Links:
Entrez Gene
Cytogenetic Map:
chr 19
19p13.3


Transcripts Names
NM_138690
XM_003403700
XM_017026243
Protein Names
Q5F0I5
O60391
Q7RTW9
Q5EAK7



GO Molecular Function

transmitter-gated ion channel activity | neurotransmitter receptor activity | glycine binding | cation binding | passive transmembrane transporter activity | neurotransmitter binding | transmembrane signaling receptor activity | carboxylic acid binding | transmembrane transporter activity | ligand-gated ion channel activity | ion gated channel activity | anion binding | amino acid binding | cation transmembrane transporter activity | signaling receptor activity | transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | glutamate receptor activity | ion binding | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | cation channel activity | inorganic cation transmembrane transporter activity | channel activity | drug binding | calcium channel activity | organic acid binding | ion channel activity | substrate-specific channel activity | small molecule binding

GO Biological Process

transmitter-gated ion channel activity | regulation of localization | establishment of localization | membrane organization | cellular process | localization | passive transmembrane transporter activity | metal ion transport | macromolecule localization | regulation of cellular process | transmembrane transporter activity | ligand-gated ion channel activity | cellular component organization | response to stimulus | ion gated channel activity | cellular localization | divalent metal ion transport | calcium ion transmembrane transport | ion transmembrane transport | protein localization to membrane | cation transmembrane transporter activity | calcium ion transmembrane transporter activity | ion transmembrane transporter activity | extracellular ligand-gated ion channel activity | protein insertion into membrane | cell communication | establishment of protein localization to membrane | cation transmembrane transport | ionotropic glutamate receptor activity | metal ion transmembrane transporter activity | cell surface receptor signaling pathway | cellular protein localization | calcium ion transport | inorganic cation transmembrane transport | establishment of protein localization | cation channel activity | transmembrane transport | signaling | inorganic cation transmembrane transporter activity | protein localization | cation transport | cellular macromolecule localization | channel activity | glutamate receptor signaling pathway | regulation of ion transport | calcium channel activity | regulation of calcium ion transport | regulation of transport | ion channel activity | ion transport | ionotropic glutamate receptor signaling pathway | substrate-specific channel activity | signal transduction

GO Cellular Component

integral component of membrane | synapse | somatodendritic compartment | cell body | cell | neuronal cell body | plasma membrane protein complex | intrinsic component of membrane | synaptic membrane | NMDA selective glutamate receptor complex | receptor complex | protein-containing complex | postsynaptic membrane | postsynapse | plasma membrane | integral component of plasma membrane | cell periphery | ionotropic glutamate receptor complex | transmembrane transporter complex | cation channel complex | ion channel complex | cell junction | membrane | intrinsic component of plasma membrane