QuickView for GRP (gene)

Gene Symbol:

GRP Homo sapiens

Full name:

gastrin releasing peptide

Synonyms:

BN, GRP-10, preproGRP, proGRP, gastrin-releasing peptide, bombesin, neuromedin C, pre-progastrin releasing peptide, prepro-GRP, testicular tissue protein Li 103

Genomic Location:

Chr 18: 55038380-55048983

Description:

This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormo...

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This gene encodes a member of the bombesin-like family of gastrin-releasing peptides. The encoded preproprotein is proteolytically processed to generate two peptides, gastrin-releasing peptide and neuromedin-C. These peptides regulate numerous functions of the gastrointestinal and central nervous systems, including release of gastrointestinal hormones, smooth muscle cell contraction, and epithelial cell proliferation. These peptides are also likely to play a role in human cancers of the lung, colon, stomach, pancreas, breast, and prostate. Alternative splicing results in multiple transcript variants, at least one of which encodes a preproprotein that is proteolytically processed.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GR_Q6_01 ,  ATF_B ,  TATAAA_TATA_01 ,  ATF_01 ,  GR_Q6 ,  CREB_Q2_01

Cytogenetic Map:

18q21.32

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