QuickView for GSN;jsessionid=C0CEDE626BAE822D64DAADA4F7194866 (gene)

Gene Symbol:

GSN Homo sapiens

Full name:

gelsolin

Synonyms:

ADF, AGEL, gelsolin, actin-depolymerizing factor, brevin

Genomic Location:

Chr 9: 123070201-123134941

Description:

The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several differe...

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The protein encoded by this gene binds to the "plus" ends of actin monomers and filaments to prevent monomer exchange. The encoded calcium-regulated protein functions in both assembly and disassembly of actin filaments. Defects in this gene are a cause of familial amyloidosis Finnish type (FAF). Multiple transcript variants encoding several different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  RFX1_01 ,  GGGAGGRR_MAZ_Q6 ,  RGAANNTTC_HSF1_01 ,  HSF1_01 ,  AP1FJ_Q2 ,  HSF_Q6 ,  AP1_Q4 ,  AP1_Q2 ,  CTTTGT_LEF1_Q2 ,  P300_01 ,  STAT5A_02

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miRNA binding sites
(Source: miRecords):

hsa-miR-124 Targeted Genes

Cytogenetic Map:

9q33.2

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