QuickView for GSS (gene)
- Gene Symbol:
- GSS
Homo sapiens - Full name:
- glutathione synthetase
- Synonyms:
- GSHS, HEL-S-64p, HEL-S-88n, glutathione synthetase, GSH synthetase, GSH-S, glutathione synthase
- Genomic Location:
- Chr 20: 32979897-33007262
- Description:
-
Glutathione is important for a variety of biological functions, including protection of cells from oxidative damage by free radicals, detoxification of xenobiotics, and membrane transport. The protein encoded by this gene functions as a homodimer to catalyze the second step of glutathione biosynthesis, which is the ATP-dependent conversion of gamma...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Saccharomyces cerevisiae , Macaca mulatta , Schizosaccharomyces pombe , Gallus gallus , Canis lupus familiaris , Danio rerio , Bos taurus , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- Cytogenetic Map:
-
20q11.22
GO Molecular Function
cofactor binding | peptide binding | modified amino acid binding | cation binding | magnesium ion binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | acid-amino acid ligase activity | glutathione synthase activity | catalytic activity | ATP binding | ligase activity, forming carbon-nitrogen bonds | anion binding | adenyl nucleotide binding | amide binding | purine nucleotide binding | identical protein binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein binding | protein homodimerization activity | protein dimerization activity | ligase activity | glutathione binding | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | metal ion binding | heterocyclic compound binding | small molecule binding
GO Biological Process
sulfur compound metabolic process | glutathione metabolic process | nervous system development | cellular process | cellular amino acid metabolic process | response to stimulus | peptide biosynthetic process | response to stress | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | glutathione synthase activity | system development | nitrogen compound metabolic process | multicellular organism development | cofactor biosynthetic process | small molecule metabolic process | cellular amide metabolic process | response to oxidative stress | biosynthetic process | peptide metabolic process | carboxylic acid metabolic process | glutathione biosynthetic process | anatomical structure development | metabolic process | organic substance metabolic process | amide biosynthetic process | organic acid metabolic process | developmental process | cellular modified amino acid metabolic process | cellular metabolic process | multicellular organismal process
GO Cellular Component
cell | cytoplasm | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | organelle | extracellular space | cytosol | intracellular
