QuickView for GSTA1 (gene)

Gene Symbol:

GSTA1 Homo sapiens

Full name:

glutathione S-transferase alpha 1

Synonyms:

GST-epsilon, GST2, GSTA1-1, GTH1, glutathione S-transferase A1, GST HA subunit 1, GST class-alpha member 1, S-(hydroxyalkyl)glutathione lyase A1, glutathione S-alkyltransferase A1, glutathione S-aryltransferase A1, glutathione S-transferase 2, glutathione S-transferase Ha subunit 1, testicular tissue protein Li 80

Genomic Location:

Chr 6: 52764347-52776616

Description:

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting c...

View Full Description

This gene encodes a member of a family of enzymes that function to add glutathione to target electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins, and products of oxidative stress. This action is an important step in detoxification of these compounds. This subfamily of enzymes has a particular role in protecting cells from reactive oxygen species and the products of peroxidation. Polymorphisms in this gene influence the ability of individuals to metabolize different drugs. This gene is located in a cluster of similar genes and pseudogenes on chromosome 6. Alternative splicing results in multiple transcript variants.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  Bos taurus ,  Pan troglodytes

External Links:

Entrez Gene

Cytogenetic Map:

6p12.2

search → result