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QuickView for GTF2H1;jsessionid=0E5DBFF4F6E4DD974C0414C201E206BF (gene)


Gene Symbol:
GTF2H1 Homo sapiens Homo sapiens
Full name:
general transcription factor IIH subunit 1
Synonyms:
BTF2, P62, TFB1, TFIIH, general transcription factor IIH subunit 1, BTF2 p62, TFIIH basal transcription factor complex p62 subunit, basic transcription factor 2 62 kDa subunit, general transcription factor IIH polypeptide 1, general transcription factor IIH, polypeptide 1, 62kDa
Genomic Location:
Chr 11: 18300719-18345153
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster C. elegans Macaca mulatta Gallus gallus Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 11
11p15.1





GO Molecular Function

hydrolase activity | protein serine/threonine kinase activity | ATPase activity | pyrophosphatase activity | RNA polymerase II CTD heptapeptide repeat kinase activity | catalytic activity | chromatin binding | nucleoside-triphosphatase activity | ATPase activity, coupled | protein binding | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, alcohol group as acceptor | hydrolase activity, acting on acid anhydrides | protein kinase activity | transferase activity | DNA-dependent ATPase activity | kinase activity | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | DNA-templated transcription, initiation | positive regulation of macromolecule biosynthetic process | RNA processing | positive regulation of cellular component organization | transcription initiation from RNA polymerase I promoter | positive regulation of cellular biosynthetic process | cellular process | 7-methylguanosine mRNA capping | global genome nucleotide-excision repair | regulation of cell cycle | positive regulation of nitrogen compound metabolic process | regulation of cellular process | regulation of metabolic process | regulation of protein complex assembly | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | cellular component organization | response to stimulus | response to stress | transcription by RNA polymerase I | cellular nitrogen compound biosynthetic process | protein serine/threonine kinase activity | protein-DNA complex assembly | cellular nitrogen compound metabolic process | nucleic acid phosphodiester bond hydrolysis | positive regulation of RNA biosynthetic process | cellular component assembly | protein modification process | mRNA metabolic process | RNA polymerase II CTD heptapeptide repeat kinase activity | cellular biosynthetic process | macromolecule modification | DNA repair | regulation of nucleic acid-templated transcription | regulation of cyclin-dependent protein serine/threonine kinase activity | nitrogen compound metabolic process | phosphorus metabolic process | cellular response to DNA damage stimulus | regulation of catalytic activity | regulation of protein serine/threonine kinase activity | regulation of phosphorylation | nucleotide-excision repair, DNA incision, 5'-to lesion | regulation of gene expression | cellular response to stress | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | positive regulation of protein complex assembly | regulation of transcription by RNA polymerase II | phosphorylation of RNA polymerase II C-terminal domain | biosynthetic process | regulation of cellular protein metabolic process | aromatic compound biosynthetic process | phosphorylation | cellular protein-containing complex assembly | nucleotide-excision repair, preincision complex stabilization | transcription elongation from RNA polymerase II promoter | protein phosphorylation | phosphate-containing compound metabolic process | regulation of cellular metabolic process | regulation of protein kinase activity | regulation of protein metabolic process | regulation of protein phosphorylation | regulation of RNA metabolic process | DNA-templated transcription, termination | protein-containing complex assembly | protein metabolic process | regulation of kinase activity | DNA metabolic process | nucleotide-excision repair, DNA incision | metabolic process | nucleotide-excision repair | regulation of RNA biosynthetic process | nucleobase-containing compound metabolic process | protein kinase activity | positive regulation of cellular component biogenesis | organic substance metabolic process | gene expression | regulation of phosphate metabolic process | transcription initiation from RNA polymerase II promoter | transcription, DNA-templated | transcription-coupled nucleotide-excision repair | regulation of transcription, DNA-templated | cellular protein metabolic process | cellular macromolecule biosynthetic process | kinase activity | cellular protein modification process | positive regulation of transcription, DNA-templated | 7-methylguanosine RNA capping | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | positive regulation of metabolic process | cellular metabolic process | mRNA processing | regulation of cellular component organization | termination of RNA polymerase I transcription | nucleotide-excision repair, preincision complex assembly | positive regulation of gene expression | macromolecule metabolic process | DNA-templated transcription, elongation | regulation of phosphorus metabolic process

GO Cellular Component

nuclear transcription factor complex | intracellular membrane-bounded organelle | catalytic complex | RNA polymerase II transcription factor complex | protein kinase complex | cell | nuclear lumen | transcription factor complex | intracellular organelle | carboxy-terminal domain protein kinase complex | protein-containing complex | nucleoplasm | transferase complex | serine/threonine protein kinase complex | membrane-bounded organelle | holo TFIIH complex | nucleus | organelle | nuclear DNA-directed RNA polymerase complex | RNA polymerase complex | membrane-enclosed lumen | core TFIIH complex | intracellular | RNA polymerase II, holoenzyme