QuickView for GUCY1A2 (gene)
- Gene Symbol:
- GUCY1A2
Homo sapiens - Full name:
- guanylate cyclase 1 soluble subunit alpha 2
- Synonyms:
- GC-SA2, GUC1A2, guanylate cyclase soluble subunit alpha-2, GCS-alpha-2, guanylate cyclase 1, soluble, alpha 2
- Genomic Location:
- Chr 11: 106063120-106394381
- Description:
-
Soluble guanylate cyclases are heterodimeric proteins that catalyze the conversion of GTP to 3',5'-cyclic GMP and pyrophosphate. The protein encoded by this gene is an alpha subunit of this complex and it interacts with a beta subunit to form the guanylate cyclase enzyme, which is activated by nitric oxide. Two transcript variants encoding differen...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , Macaca mulatta , Pan troglodytes , Canis lupus familiaris , Danio rerio , Bos taurus , Gallus gallus
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
CACGTG_MYC_Q2 , NGFIC_01 , MAX_01 , EGR2_01 , AP2_Q6 , TTGTTT_FOXO4_01 , IK2_01 , USF2_Q6 , AAGCACA_MIR218
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
11q22.3
GO Molecular Function
guanyl ribonucleotide binding | cofactor binding | ribonucleoside binding | ribonucleotide binding | nucleotide binding | carbohydrate derivative binding | anion binding | purine nucleotide binding | ion binding | organic cyclic compound binding | purine nucleoside binding | purine ribonucleoside triphosphate binding | tetrapyrrole binding | protein binding | GTP binding | nucleoside binding | purine ribonucleotide binding | heme binding | heterocyclic compound binding | guanyl nucleotide binding | small molecule binding
GO Biological Process
intracellular signal transduction | cellular process | regulation of cellular process | response to stimulus | positive regulation of nitric oxide mediated signal transduction | regulation of signal transduction | positive regulation of intracellular signal transduction | cell communication | positive regulation of signal transduction | regulation of intracellular signal transduction | regulation of cell communication | signaling | regulation of nitric oxide mediated signal transduction | positive regulation of signaling | signal transduction | regulation of signaling
GO Cellular Component
