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QuickView for Galpha (gene)

Gene Symbol:
SUCLG1 Homo sapiens Homo sapiens
Full name:
succinate-CoA ligase alpha subunit
GALPHA, MTDPS9, SUCLA1, succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, SCS-alpha, succinyl-CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial, succinyl-CoA ligase [GDP-forming] subunit alpha, mitochondrial, succinyl-CoA synthetase subunit alpha
Genomic Location:
Chr 2: 84504163-84540097
This gene encodes the alpha subunit of the heterodimeric enzyme succinate coenzyme A ligase. This enzyme is targeted to the mitochondria and catalyzes the conversion of succinyl CoA and ADP or GDP to succinate and ATP or GTP. Mutations in this gene are the cause of the metabolic disorder fatal infantile lactic acidosis and mitochondrial DNA depleti...
Mus musculus Rattus norvegicus D. melanogaster C. elegans Saccharomyces cerevisiae Macaca mulatta Schizosaccharomyces pombe Gallus gallus Danio rerio Pan troglodytes Canis lupus familiaris Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 2

Transcripts Names
Protein Names

GO Molecular Function

GDP binding | guanyl ribonucleotide binding | cofactor binding | ribonucleoside binding | acid-thiol ligase activity | nucleic acid binding | ribonucleotide binding | succinate-CoA ligase activity | nucleotide binding | carbohydrate derivative binding | catalytic activity | anion binding | purine nucleotide binding | ion binding | nucleobase-containing compound kinase activity | organic cyclic compound binding | purine nucleoside binding | nucleoside diphosphate kinase activity | ligase activity | succinate-CoA ligase (ADP-forming) activity | transferase activity, transferring phosphorus-containing groups | phosphotransferase activity, phosphate group as acceptor | transferase activity | nucleoside binding | purine ribonucleotide binding | kinase activity | heterocyclic compound binding | succinate-CoA ligase (GDP-forming) activity | guanyl nucleotide binding | small molecule binding | RNA binding

GO Biological Process

purine ribonucleotide metabolic process | succinate metabolic process | tricarboxylic acid cycle | sulfur compound metabolic process | generation of precursor metabolites and energy | aerobic respiration | cellular process | dicarboxylic acid metabolic process | nucleotide metabolic process | cellular respiration | ribose phosphate metabolic process | nucleoside triphosphate metabolic process | ribonucleotide metabolic process | organic cyclic compound metabolic process | cellular aromatic compound metabolic process | succinyl-CoA metabolic process | purine nucleotide metabolic process | cellular nitrogen compound biosynthetic process | cellular nitrogen compound metabolic process | cofactor metabolic process | cellular biosynthetic process | nitrogen compound metabolic process | antibiotic metabolic process | phosphorus metabolic process | acyl-CoA metabolic process | organophosphate metabolic process | nucleotide phosphorylation | small molecule metabolic process | cellular amide metabolic process | nucleobase-containing small molecule metabolic process | biosynthetic process | aromatic compound biosynthetic process | phosphorylation | nucleobase-containing compound kinase activity | nucleoside triphosphate biosynthetic process | phosphate-containing compound metabolic process | nucleoside diphosphate kinase activity | drug metabolic process | carboxylic acid metabolic process | nucleoside diphosphate metabolic process | tricarboxylic acid metabolic process | metabolic process | oxidation-reduction process | citrate metabolic process | nucleobase-containing compound metabolic process | organic substance metabolic process | organic acid metabolic process | energy derivation by oxidation of organic compounds | kinase activity | carbohydrate derivative metabolic process | heterocycle metabolic process | cellular metabolic process | nucleoside diphosphate phosphorylation

GO Cellular Component

mitochondrial matrix | intracellular membrane-bounded organelle | catalytic complex | cell | cytoplasm | intracellular organelle | protein-containing complex | plasma membrane | mitochondrion | membrane-bounded organelle | organelle | tricarboxylic acid cycle enzyme complex | cell periphery | succinate-CoA ligase complex | membrane-enclosed lumen | succinate-CoA ligase complex (GDP-forming) | cytosol | intracellular | membrane