QuickView for Gata4 (gene)

Gene Symbol:

GATA4 Homo sapiens

Full name:

GATA binding protein 4

Synonyms:

ASD2, TACHD, TOF, VSD1, transcription factor GATA-4, GATA-binding factor 4

Genomic Location:

Chr 8: 11599162-11654918

Description:

This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. M...

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This gene encodes a member of the GATA family of zinc-finger transcription factors. Members of this family recognize the GATA motif which is present in the promoters of many genes. This protein is thought to regulate genes involved in embryogenesis and in myocardial differentiation and function, and is necessary for normal testicular development. Mutations in this gene have been associated with cardiac septal defects. Additionally, alterations in gene expression have been associated with several cancer types. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  HNF4ALPHA_Q6 ,  FREAC7_01 ,  GATA1_03 ,  RYTTCCTG_ETS2_B ,  ARNT_01 ,  NFAT_Q6 ,  AML_Q6 ,  YTATTTTNR_MEF2_02 ,  CACGTG_MYC_Q2 ,  NFKAPPAB_01 ,  ARNT_02 ,  COUP_01 ,  NFKAPPAB65_01 ,  HNF4_DR1_Q3 ,  HNF4_01 ,  CDPCR3HD_01 ,  MYCMAX_02 ,  MEF2_01 ,  P53_02 ,  PXR_Q2 ,  HNF4_Q6 ,  CDPCR1_01 ,  HMEF2_Q6 ,  NCX_01 ,  CEBP_C ,  CAGTATT_MIR200B_MIR200C_MIR429 ,  GATA1_05 ,  CREL_01 ,  ER_Q6_02 ,  NFKB_Q6_01 ,  NFKB_Q6 ,  NFKB_C ,  HNF4_01_B ,  GGGNNTTTCC_NFKB_Q6_01 ,  MEF2_Q6_01

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-200b ,  Predicted Gene Targets for miR-208 ,  Predicted Gene Targets for miR-26 ,  Predicted Gene Targets for miR-499

Cytogenetic Map:

8p23.1

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