QuickView for Geranyltranstransferase (gene)

Gene Symbol:

GGPS1 Homo sapiens

Full name:

geranylgeranyl diphosphate synthase 1

Synonyms:

GGPPS, GGPPS1, geranylgeranyl pyrophosphate synthase, (2E,6E)-farnesyl diphosphate synthase, GGPP synthase, GGPPSase, dimethylallyltranstransferase, farnesyl diphosphate synthase, farnesyltranstransferase, geranyltranstransferase

Genomic Location:

Chr 1: 233558376-233574470

Description:

This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear horm...

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This gene is a member of the prenyltransferase family and encodes a protein with geranylgeranyl diphosphate (GGPP) synthase activity. The enzyme catalyzes the synthesis of GGPP from farnesyl diphosphate and isopentenyl diphosphate. GGPP is an important molecule responsible for the C20-prenylation of proteins and for the regulation of a nuclear hormone receptor. Alternate transcriptional splice variants, both protein-coding and non-protein-coding, have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Saccharomyces cerevisiae ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SRY_01 ,  WHN_B ,  CREB_Q3 ,  CEBPDELTA_Q6 ,  ATF3_Q6 ,  HMX1_01 ,  TTGTTT_FOXO4_01 ,  DR4_Q2

Cytogenetic Map:

1q42.3

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