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QuickView for Glycodiazine (compound)
PubChem
| Name: | glymidine |
|---|---|
| PubChem Compound ID: | 9565 |
| Molecular formula: | C13H15N3O4S |
| Molecular weight: | 309.342 g/mol |
| Synonyms: |
Glymidinum; GLYMIDINE; 5-25-12-00549 (Beilstein Handbook Reference); 5-beta-(Methoxyethoxy)-2-(phenylsulfonylamido)pyrimidine; BRN 0552655; EINECS 206-426-5; Glycodiazine Glymidine; 339-44-6; Benzenesulfonamide, N-(5-(2-methoxyethoxy)-2-pyrimidinyl)-; 2-Benzolsulfonamido-5-beta-methoxy-aethoxy-pyrimidine [German].
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DrugBank
Identification
| Name: | glymidine |
|---|---|
| Name (isomeric): | DB01382 |
| Drug Type: | small molecule |
| Synonyms: |
Glidiazine; Glymidine
|
| Category: | Hypoglycemic Agents |
| CAS number: | 339-44-6 |
Pharmacology
| Indication: | Glycodiazine is used concomitantly with insulin for the treatment of noninsulin-dependent (type 2) diabetes mellitus. |
|---|---|
| Pharmacology: | Glycodiazine is used with diet to lower blood glucose by increasing the secretion of insulin from pancreas and increasing the sensitivity of peripheral tissues to insulin. |
| Mechanism of Action: |
The mechanism of action of glycodiazine in lowering blood glucose appears to be dependent on stimulating the release of insulin from functioning pancreatic beta cells, and increasing sensitivity of peripheral tissues to insulin. Glycodiazine likely binds to ATP-sensitive potassium channel receptors on the pancreatic cell surface, reducing potassium...
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| Absorption: | Rapidly and completely absorbed following oral administration. |
| Protein binding: | 90% bound to plasma proteins. |
| Half Life: | 4 hours. |
| Toxicity: | Severe hypoglycemic reactions with coma, seizure, or other neurological impairment. |
| Affected organisms: | Humans and other mammals |
Interactions
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Targets
