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QuickView for GnRH1 (gene)

Gene Symbol:
GNRH1 Homo sapiens Homo sapiens
Full name:
gonadotropin releasing hormone 1
GNRH, GRH, LHRH, LNRH, progonadoliberin-1, GnRH-associated peptide 1, gonadotropin-releasing hormone 1 (luteinizing-releasing hormone), leuteinizing-releasing hormone, luliberin I, prolactin release-inhibiting factor
Genomic Location:
Chr 8: 25332691-25338473
This gene encodes a preproprotein that is proteolytically processed to generate a peptide that is a member of the gonadotropin-releasing hormone (GnRH) family of peptides. Alternative splicing results in multiple transcript variants, at least one of which is secreted and then cleaved to generate gonadoliberin-1 and GnRH-associated peptide 1. Gonado...
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Pan troglodytes Bos taurus Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 8

Transcripts Names
Protein Names

GO Molecular Function

gonadotropin hormone-releasing hormone activity | hormone receptor binding | signaling receptor binding | gonadotropin-releasing hormone receptor binding | hormone activity | molecular function regulator | peptide hormone receptor binding | protein binding | receptor regulator activity | receptor ligand activity

GO Biological Process

negative regulation of leukocyte activation | gonadotropin hormone-releasing hormone activity | negative regulation of immune system process | regulation of neurogenesis | male sex determination | response to lipopolysaccharide | developmental process involved in reproduction | regulation of cell development | regulation of localization | regulation of programmed cell death | regulation of immune system process | response to hormone | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | response to potassium ion | response to metal ion | cell differentiation | nervous system development | response to drug | neurogenesis | generation of neurons | response to antibiotic | cellular process | regulation of neuron migration | regulation of cell motility | female pregnancy | multicellular organismal reproductive process | negative regulation of apoptotic process | negative regulation of cell migration | negative regulation of T cell proliferation | response to inorganic substance | response to peptide hormone | regulation of cell differentiation | response to prostaglandin | negative regulation of cell motility | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | negative regulation of mononuclear cell proliferation | response to stimulus | negative regulation of cell adhesion | negative regulation of lymphocyte activation | regulation of cell proliferation | ovulation cycle | response to peptide | reproduction | response to alcohol | rhythmic process | response to molecule of bacterial origin | hormone activity | G-protein coupled receptor signaling pathway | regulation of ovarian follicle development | negative regulation of immature T cell proliferation | regulation of cell adhesion | cell-cell signaling | molecular function regulator | response to ethanol | response to nitrogen compound | response to external biotic stimulus | system development | reproductive process | regulation of signal transduction | multicellular organism development | response to fatty acid | regulation of T cell activation | regulation of gene expression | response to prostaglandin E | regulation of female gonad development | response to ketone | response to lipid | regulation of lymphocyte activation | negative regulation of T cell activation | regulation of cell migration | response to corticosteroid | regulation of cellular component movement | sex determination | response to toxic substance | response to bacterium | negative regulation of cell-cell adhesion | cell communication | response to testosterone | negative regulation of cell activation | regulation of locomotion | multicellular organism reproduction | regulation of signaling receptor activity | receptor regulator activity | response to organic substance | anatomical structure development | negative regulation of leukocyte proliferation | negative regulation of programmed cell death | response to prolactin | receptor ligand activity | negative regulation of neuron migration | regulation of cell activation | negative regulation of cellular component movement | estrous cycle | regulation of cell communication | signaling | response to organic cyclic compound | regulation of T cell proliferation | response to biotic stimulus | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of cell proliferation | regulation of cell-cell adhesion | response to organonitrogen compound | negative regulation of lymphocyte proliferation | regulation of cell death | response to steroid hormone | negative regulation of cell death | negative regulation of cell development | aging | negative regulation of locomotion | negative regulation of cell differentiation | response to other organism | signal transduction | regulation of signaling | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

cytoplasmic side of rough endoplasmic reticulum membrane | rough endoplasmic reticulum membrane | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | organelle membrane | cytoplasmic vesicle | cell body | neurosecretory vesicle | cell | cytoplasmic side of membrane | neuronal cell body | distal axon | cytoplasm | intracellular organelle | endoplasmic reticulum | dendritic tree | presynapse | nuclear outer membrane-endoplasmic reticulum membrane network | cell projection | endomembrane system | endoplasmic reticulum membrane | perikaryon | Golgi-associated vesicle | cytoplasmic side of endoplasmic reticulum membrane | vesicle | mitochondrion | granular vesicle | extracellular region | membrane-bounded organelle | organelle | axon terminus | extracellular space | axon | neuron projection terminus | rough endoplasmic reticulum | intracellular vesicle | intracellular | membrane