Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for Gpr161 (gene)


Gene Symbol:
GPR161 Homo sapiens Homo sapiens
Full name:
G protein-coupled receptor 161
Synonyms:
RE2, G-protein coupled receptor 161, G-protein coupled receptor RE2
Genomic Location:
Chr 1: 166320621-166372248
Description:
The protein encoded by this gene is an orphan G protein-coupled receptor whose ligand is unknown. This gene is overexpressed in triple-negative breast cancer, and disruption of this gene slows the proliferation of basal breast cancer cells. Therefore, this gene is a potential drug target for triple-negative breast cancer.
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Canis lupus familiaris Pan troglodytes Bos taurus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 1
1q24.2





GO Molecular Function

transmembrane signaling receptor activity | G-protein coupled receptor activity | signaling receptor activity

GO Biological Process

negative regulation of embryonic development | intracellular signal transduction | negative regulation of cellular process | negative regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | cellular process | negative regulation of signaling | regulation of embryonic development | regulation of smoothened signaling pathway | regulation of cellular process | G-protein coupled receptor activity | response to stimulus | G-protein coupled receptor signaling pathway | regulation of signal transduction | multicellular organism development | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | adenylate cyclase-activating G-protein coupled receptor signaling pathway | regulation of smoothened signaling pathway involved in dorsal/ventral neural tube patterning | second-messenger-mediated signaling | cell communication | cyclic-nucleotide-mediated signaling | cAMP-mediated signaling | anatomical structure development | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of signal transduction | signaling | regulation of nervous system development | regulation of developmental process | developmental process | negative regulation of smoothened signaling pathway | signal transduction | regulation of signaling | multicellular organismal process

GO Cellular Component

integral component of membrane | ciliary membrane | endocytic vesicle membrane | organelle membrane | cell projection membrane | cytoplasmic vesicle | cell | intrinsic component of membrane | cytoplasm | intracellular organelle | cell projection | recycling endosome | endomembrane system | plasma membrane | cilium | vesicle | endosome | membrane-bounded organelle | organelle | vesicle membrane | cell periphery | intracellular vesicle | endocytic vesicle | intracellular | membrane | cytoplasmic vesicle membrane