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QuickView for Grm2 (gene)


Gene Symbol:
GRM2 Homo sapiens Homo sapiens
Full name:
glutamate metabotropic receptor 2
Synonyms:
GLUR2, GPRC1B, MGLUR2, mGlu2, metabotropic glutamate receptor 2, glutamate receptor homolog, glutamate receptor, metabotropic 2
Genomic Location:
Chr 3: 51718004-51727669
Description:
L-glutamate is the major excitatory neurotransmitter in the central nervous system and activates both ionotropic and metabotropic glutamate receptors. Glutamatergic neurotransmission is involved in most aspects of normal brain function and can be perturbed in many neuropathologic conditions. The metabotropic glutamate receptors are a family of G pr...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 3
3p21.2





GO Molecular Function

channel regulator activity | transmembrane signaling receptor activity | G-protein coupled receptor activity | molecular function regulator | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity | signaling receptor activity | glutamate receptor activity | protein binding | calcium channel regulator activity | group II metabotropic glutamate receptor activity

GO Biological Process

establishment of localization | adenylate cyclase-inhibiting G-protein coupled glutamate receptor signaling pathway | cellular process | secretion | channel regulator activity | localization | chemical synaptic transmission | dicarboxylic acid transport | anion transport | regulation of cellular process | adenylate cyclase-inhibiting G-protein coupled receptor signaling pathway | G-protein coupled receptor activity | negative regulation of lyase activity | response to stimulus | acid secretion | secretion by cell | G-protein coupled receptor signaling pathway | modulation of chemical synaptic transmission | cell-cell signaling | molecular function regulator | negative regulation of catalytic activity | regulation of synaptic transmission, glutamatergic | adenylate cyclase-modulating G-protein coupled receptor signaling pathway | regulation of catalytic activity | adenylate cyclase inhibiting G-protein coupled glutamate receptor activity | organic substance transport | synaptic signaling | organic acid transport | organic anion transport | negative regulation of adenylate cyclase activity | regulation of cyclase activity | G-protein coupled glutamate receptor signaling pathway | cell communication | amino acid transport | calcium channel regulator activity | cell surface receptor signaling pathway | regulation of adenylate cyclase activity | group II metabotropic glutamate receptor activity | G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger | regulation of cell communication | negative regulation of molecular function | signaling | carboxylic acid transport | glutamate receptor signaling pathway | glutamate secretion | ion transport | signal transduction | regulation of signaling

GO Cellular Component

presynaptic membrane | integral component of membrane | dendrite | synapse | neuron projection | somatodendritic compartment | cell | intrinsic component of membrane | synaptic membrane | dendritic tree | presynapse | cell projection | plasma membrane | integral component of plasma membrane | cell periphery | axon | intracellular | cell junction | membrane | intrinsic component of plasma membrane