QuickView for GroES (gene)

Gene Symbol:

HSPE1 Homo sapiens

Full name:

heat shock protein family E (Hsp10) member 1

Synonyms:

CPN10, EPF, GROES, HSP10, 10 kDa heat shock protein, mitochondrial, 10 kDa chaperonin, chaperonin 10, early-pregnancy factor, heat shock 10kD protein 1 (chaperonin 10), heat shock 10kDa protein 1

Genomic Location:

Chr 2: 198073365-198076416

Description:

This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head ori...

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This gene encodes a major heat shock protein which functions as a chaperonin. Its structure consists of a heptameric ring which binds to another heat shock protein in order to form a symmetric, functional heterodimer which enhances protein folding in an ATP-dependent manner. This gene and its co-chaperonin, HSPD1, are arranged in a head-to-head orientation on chromosome 2. Naturally occurring read-through transcription occurs between this locus and the neighboring locus MOBKL3.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Schizosaccharomyces pombe ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

USF_Q6 ,  STAT1_02 ,  CACGTG_MYC_Q2 ,  E4BP4_01 ,  TTCNRGNNNNTTC_HSF_Q6 ,  STAT1_03 ,  TGACCTY_ERR1_Q2 ,  WHN_B ,  CREB_Q3 ,  HNF4_DR1_Q3 ,  GGGAGGRR_MAZ_Q6 ,  STAT_Q6 ,  HNF4_01 ,  RGAANNTTC_HSF1_01 ,  CATGTAA_MIR496 ,  DR1_Q3 ,  TTCYRGAA_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  USF_C ,  GCGNNANTTCC_UNKNOWN ,  HSF_Q6 ,  RORA1_01 ,  NMYC_01 ,  COUP_DR1_Q6 ,  CCGNMNNTNACG_UNKNOWN ,  RCGCANGCGY_NRF1_Q6 ,  ERR1_Q2 ,  TGACCTTG_SF1_Q6

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-1 ,  Predicted Gene Targets for miR-496

Cytogenetic Map:

2q33.1

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