QuickView for H2A.Z (gene)
- Gene Symbol:
- H2AFZ
Homo sapiens - Full name:
- H2A histone family member Z
- Synonyms:
- H2A.Z-1, H2A.z, H2A/z, H2AZ, histone H2A.Z, H2AZ histone
- Genomic Location:
- Chr 4: 101088267-101090535
- Description:
-
Histones are basic nuclear proteins that are responsible for the nucleosome structure of the chromosomal fiber in eukaryotes. Nucleosomes consist of approximately 146 bp of DNA wrapped around a histone octamer composed of pairs of each of the four core histones (H2A, H2B, H3, and H4). The chromatin fiber is further compacted through the interaction...
- Orthologs:
- Mus musculus , Rattus norvegicus , D. melanogaster , C. elegans , Macaca mulatta , Bos taurus , Danio rerio , Gallus gallus , Pan troglodytes , Canis lupus familiaris
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites: -
PR_Q2 , TFIIA_Q6 , MYOD_01 , E2F1_Q4_01 , YGTCCTTGR_UNKNOWN , CACGTG_MYC_Q2 , E2F4DP1_01 , CAGTGTT_MIR141_MIR200A , E2F_Q6_01 , ARNT_02
- miRNA binding sites
(Source: TargetScan):
- Cytogenetic Map:
-
4q23
GO Molecular Function
sequence-specific DNA binding | transcription regulatory region DNA binding | core promoter binding | enhancer binding | nucleosome binding | proximal promoter sequence-specific DNA binding | nucleic acid binding | protein-containing complex binding | chromatin binding | RNA polymerase II core promoter sequence-specific DNA binding | enhancer sequence-specific DNA binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | protein heterodimerization activity | nucleosomal DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | protein binding | RNA polymerase II proximal promoter sequence-specific DNA binding | double-stranded DNA binding | chromatin DNA binding | protein dimerization activity | RNA polymerase II regulatory region sequence-specific DNA binding | RNA polymerase II distal enhancer sequence-specific DNA binding | core promoter sequence-specific DNA binding | heterocyclic compound binding
GO Biological Process
positive regulation of macromolecule biosynthetic process | response to hormone | positive regulation of cellular biosynthetic process | cellular process | chromatin organization | response to estradiol | positive regulation of nitrogen compound metabolic process | regulation of cellular process | cellular response to lipid | regulation of metabolic process | cellular component organization | response to stimulus | cellular response to organic cyclic compound | positive regulation of RNA biosynthetic process | regulation of nucleic acid-templated transcription | cellular response to hormone stimulus | regulation of gene expression | response to lipid | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | regulation of cellular metabolic process | regulation of RNA metabolic process | response to organic substance | regulation of RNA biosynthetic process | cellular response to estradiol stimulus | regulation of transcription, DNA-templated | response to organic cyclic compound | organelle organization | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | chromosome organization | cellular response to organic substance | positive regulation of gene expression
GO Cellular Component
nuclear euchromatin | chromosome | intracellular membrane-bounded organelle | cell | nuclear lumen | sex chromosome | nucleosome | intracellular organelle | euchromatin | protein-containing complex | protein-DNA complex | Barr body | chromatin | nuclear chromosome | vesicle | extracellular exosome | extracellular region | membrane-bounded organelle | extracellular vesicle | heterochromatin | nucleus | organelle | extracellular space | nuclear heterochromatin | membrane-enclosed lumen | X chromosome | nuclear chromatin | intracellular
