QuickView for HAGH (gene)

Gene Symbol:

HAGH Homo sapiens

Full name:

hydroxyacylglutathione hydrolase

Synonyms:

GLO2, GLX2, GLXII, HAGH1, hydroxyacylglutathione hydrolase, mitochondrial, glx II, glyoxalase II, hydroxyacylglutathione hydroxylase

Genomic Location:

Chr 16: 1799105-1817196

Description:

The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene.

The enzyme encoded by this gene is classified as a thiolesterase and is responsible for the hydrolysis of S-lactoyl-glutathione to reduced glutathione and D-lactate. Three transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Saccharomyces cerevisiae ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  CEBP_Q2_01 ,  HNF4_DR1_Q3 ,  CEBP_01 ,  CCTGCTG_MIR214 ,  TCF11_01

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-214

Cytogenetic Map:

16p13.3

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