QuickView for HCK;jsessionid=E0DD44BDB8F15864C52FDBC3CBD2D2AF (gene)

Gene Symbol:

HCK Homo sapiens

Full name:

HCK proto-oncogene, Src family tyrosine kinase

Synonyms:

JTK9, p59Hck, p61Hck, tyrosine-protein kinase HCK, hematopoietic cell kinase, hemopoietic cell kinase, p59-HCK/p60-HCK

Genomic Location:

Chr 20: 30103718-30153320

Description:

The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of ne...

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The protein encoded by this gene is a member of the Src family of tyrosine kinases. This protein is primarily hemopoietic, particularly in cells of the myeloid and B-lymphoid lineages. It may help couple the Fc receptor to the activation of the respiratory burst. In addition, it may play a role in neutrophil migration and in the degranulation of neutrophils. Multiple isoforms with different subcellular distributions are produced due to both alternative splicing and the use of alternative translation initiation codons, including a non-AUG (CUG) codon.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TAL1ALPHAE47_01 ,  TAL1BETAE47_01 ,  GGGYGTGNY_UNKNOWN ,  ER_Q6_02

Cytogenetic Map:

20q11.21

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