QuickView for HDAC (gene)

Gene Symbol:

HDAC9 Homo sapiens

Full name:

histone deacetylase 9

Synonyms:

HD7, HD7b, HD9, HDAC, HDAC7, HDAC7B, HDAC9B, HDAC9FL, HDRP, MITR, histone deacetylase 9, MEF-2 interacting transcription repressor (MITR) protein, histone deacetylase 4/5-related protein, histone deacetylase 7B

Genomic Location:

Chr 7: 18501894-19003518

Description:

Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to ...

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Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene has sequence homology to members of the histone deacetylase family. This gene is orthologous to the Xenopus and mouse MITR genes. The MITR protein lacks the histone deacetylase catalytic domain. It represses MEF2 activity through recruitment of multicomponent corepressor complexes that include CtBP and HDACs. This encoded protein may play a role in hematopoiesis. Multiple alternatively spliced transcripts have been described for this gene but the full-length nature of some of them has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

OCT1_07 ,  TGANTCA_AP1_C ,  OCT1_B ,  STAT1_02 ,  FOXJ2_02 ,  OCT1_04 ,  RSRFC4_01 ,  OCT1_01 ,  GATA3_01 ,  FOXO4_01 ,  YATGNWAAT_OCT_C ,  OCT_Q6 ,  POU3F2_01 ,  YTATTTTNR_MEF2_02 ,  CATTGTYY_SOX9_B1 ,  GCANCTGNY_MYOD_Q6 ,  NGFIC_01 ,  TGTGTGA_MIR377 ,  RSRFC4_Q2 ,  HP1SITEFACTOR_Q6 ,  WGTTNNNNNAAA_UNKNOWN ,  TGTTTAC_MIR30A5P_MIR30C_MIR30D_MIR30B_MIR30E5P ,  AMEF2_Q6 ,  FAC1_01 ,  STAT1_03 ,  GGGCATT_MIR365 ,  PBX1_01 ,  CTAWWWATA_RSRFC4_Q2 ,  RFX1_01 ,  EGR2_01 ,  OCT_C ,  WTGAAAT_UNKNOWN ,  MEF2_02 ,  TATAAA_TATA_01 ,  AR_Q6 ,  SOX9_B1 ,  PAX2_01 ,  MEF2_01 ,  CAGGTG_E12_Q6 ,  E47_02 ,  MYOD_Q6 ,  AREB6_01 ,  GTGCCAA_MIR96 ,  OCT1_03 ,  NKX25_02 ,  POU1F1_Q6 ,  GATA1_02 ,  HMEF2_Q6 ,  RORA1_01 ,  GTGCCTT_MIR506 ,  OCT1_02 ,  POU3F2_02 ,  TTGTTT_FOXO4_01 ,  CEBP_C ,  WWTAAGGC_UNKNOWN ,  MEF2_03 ,  WTTGKCTG_UNKNOWN ,  CTGCAGY_UNKNOWN ,  RORA2_01 ,  TBP_01 ,  YWATTWNNRGCT_UNKNOWN ,  CAGCTG_AP4_Q5 ,  FOXM1_01 ,  COREBINDINGFACTOR_Q6 ,  EGR3_01 ,  CP2_01

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Cytogenetic Map:

7p21.1

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