QuickView for HERC1;jsessionid=FCEDDC0DB34DE95BDC07932FCE6BFE59 (gene)

Gene Symbol:

HERC1 Homo sapiens

Full name:

HECT and RLD domain containing E3 ubiquitin protein ligase family member 1

Synonyms:

MDFPMR, p532, p619, probable E3 ubiquitin-protein ligase HERC1, HECT domain and RCC1-like domain-containing protein 1, HECT-type E3 ubiquitin transferase HERC1, guanine nucleotide exchange factor p532, hect (homologous to the E6-AP (UBE3A) carboxyl terminus) domain and RCC1 (CHC1)-like domain (RLD) 1

Genomic Location:

Chr 15: 61687870-61913200

Description:

This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes.

This gen encodes a member of the HERC protein family. This protein stimulates guanine nucleotide exchange on ARF1 and Rab proteins. This protein may be involved in membrane transport processes.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SRF_Q6 ,  CTTTGA_LEF1_Q2 ,  WHN_B ,  TATAAA_TATA_01 ,  TITF1_Q3 ,  ATF3_Q6 ,  GGGCGGR_SP1_Q6 ,  SRF_Q4 ,  GCGNNANTTCC_UNKNOWN ,  CTGCAGY_UNKNOWN ,  TGATTTRY_GFI1_01 ,  CCGNMNNTNACG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  SRF_C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-493-5p ,  Predicted Gene Targets for miR-378

Cytogenetic Map:

15q22.31

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