QuickView for HMGN3;jsessionid=FAC6F26501ACC752D755F6B36741828C (gene)

Gene Symbol:

HMGN3 Homo sapiens

Full name:

high mobility group nucleosomal binding domain 3

Synonyms:

PNAS-24, PNAS-25, TRIP7, high mobility group nucleosome-binding domain-containing protein 3, TR-interacting protein 7, thyroid hormone receptor interacting protein 7

Genomic Location:

Chr 6: 79967681-80001174

Description:

The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding di...

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The protein encoded by this gene binds thyroid hormone receptor beta in the presence of thyroid hormone. The encoded protein, a member of the HMGN protein family, is thought to reduce the compactness of the chromatin fiber in nucleosomes, thereby enhancing transcription from chromatin templates. Alternatively spliced transcript variants encoding different isoforms have been found for this gene. There is a related pseudogene on chromosome 1.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Danio rerio ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

NFAT_Q4_01 ,  TGGAAA_NFAT_Q4_01 ,  EFC_Q6 ,  AP3_Q6 ,  CATTGTYY_SOX9_B1 ,  TCTAGAG_MIR517 ,  TATAAA_TATA_01 ,  GGGYGTGNY_UNKNOWN ,  NFY_Q6_01 ,  P53_02 ,  HFH8_01 ,  RNGTGGGC_UNKNOWN ,  CEBP_Q3 ,  CCTGCTG_MIR214 ,  TTGTTT_FOXO4_01 ,  RGAGGAARY_PU1_Q6 ,  PAX5_01 ,  TGGTGCT_MIR29A_MIR29B_MIR29C

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-214 ,  Predicted Gene Targets for miR-137 ,  Predicted Gene Targets for miR-29

Cytogenetic Map:

6q14.1

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