QuickView for HNRNPF;jsessionid=6A6C250B9D09313D3DBBA9DB8CCCA049 (gene)

Gene Symbol:

HNRNPF Homo sapiens

Full name:

heterogeneous nuclear ribonucleoprotein F

Synonyms:

HNRPF, OK/SW-cl.23, mcs94-1, heterogeneous nuclear ribonucleoprotein F, HnRNP F protein, nucleolin-like protein mcs94-1

Genomic Location:

Chr 10: 43201071-43224702

Description:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism ...

View Full Description

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins that complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and regulate alternative splicing, polyadenylation, and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs which have guanosine-rich sequences. This protein is very similar to the family member hnRPH. Multiple alternatively spliced variants, encoding the same protein, have been identified.

View Less

Orthologs:

Mus musculus ,  Rattus norvegicus ,  C. elegans ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

TGGAAA_NFAT_Q4_01 ,  ACTGTAG_MIR139 ,  TTTGCAC_MIR19A_MIR19B ,  MAZ_Q6 ,  EFC_Q6 ,  MYC_Q2 ,  CACGTG_MYC_Q2 ,  CAGTGTT_MIR141_MIR200A ,  GTACTGT_MIR101 ,  MYB_Q5_01 ,  CTCNANGTGNY_UNKNOWN ,  ACTGTGA_MIR27A_MIR27B ,  CTTTGTA_MIR524 ,  RFX1_02 ,  GGGCGGR_SP1_Q6 ,  TGCCAAR_NF1_Q6 ,  ATACTGT_MIR144 ,  MYB_Q6 ,  USF2_Q6 ,  GTTNYYNNGGTNA_UNKNOWN ,  AGGAAGC_MIR5163P ,  GGGTGGRR_PAX4_03 ,  MYB_Q3

View More

View Less

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-101 ,  Predicted Gene Targets for miR-128 ,  Predicted Gene Targets for miR-139 ,  Predicted Gene Targets for miR-144 ,  Predicted Gene Targets for miR-19 ,  Predicted Gene Targets for miR-141 ,  Predicted Gene Targets for miR-224 ,  Predicted Gene Targets for miR-27 ,  Predicted Gene Targets for miR-539 ,  Predicted Gene Targets for miR-29 ,  Predicted Gene Targets for miR-488 ,  Predicted Gene Targets for miR-495

View More

View Less

Cytogenetic Map:

10q11.21

search → result