QuickView for HNRNPM;jsessionid=71A56389FA703FE693C9A4EEC1FAD010 (gene)

Gene Symbol:

HNRNPM Homo sapiens

Full name:

heterogeneous nuclear ribonucleoprotein M

Synonyms:

CEAR, HNRNPM4, HNRPM, HNRPM4, HTGR1, NAGR1, hnRNP M, heterogeneous nuclear ribonucleoprotein M, CEA receptor, N-acetylglucosamine receptor 1, heterogenous nuclear ribonucleoprotein M4, hnRNA-binding protein M4

Genomic Location:

Chr 19: 8415803-8459998

Description:

This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and ...

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This gene belongs to the subfamily of ubiquitously expressed heterogeneous nuclear ribonucleoproteins (hnRNPs). The hnRNPs are RNA binding proteins and they complex with heterogeneous nuclear RNA (hnRNA). These proteins are associated with pre-mRNAs in the nucleus and appear to influence pre-mRNA processing and other aspects of mRNA metabolism and transport. While all of the hnRNPs are present in the nucleus, some seem to shuttle between the nucleus and the cytoplasm. The hnRNP proteins have distinct nucleic acid binding properties. The protein encoded by this gene has three repeats of quasi-RRM domains that bind to RNAs. This protein also constitutes a monomer of the N-acetylglucosamine-specific receptor which is postulated to trigger selective recycling of immature GlcNAc-bearing thyroglobulin molecules. Alternative splicing results in multiple transcript variants.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  Macaca mulatta ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Danio rerio

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

USF_Q6 ,  CACGTG_MYC_Q2 ,  TTTGTAG_MIR520D ,  TGAGATT_MIR216 ,  GACTGTT_MIR212_MIR132 ,  WCAANNNYCAG_UNKNOWN ,  CTTTGT_LEF1_Q2 ,  ACCATTT_MIR522

miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-132 ,  Predicted Gene Targets for miR-216

Cytogenetic Map:

19p13.2

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