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QuickView for HOXD10;jsessionid=910A938F17301737C429CF3ADC804AB7 (gene)


Gene Symbol:
HOXD10 Homo sapiens Homo sapiens
Full name:
homeobox D10
Synonyms:
HOX4, HOX4D, HOX4E, Hox-4.4, homeobox protein Hox-D10, homeo box 4D, homeo box D10, homeobox protein Hox-4D, homeobox protein Hox-4E
Genomic Location:
Chr 2: 176689738-176692916
Description:
This gene is a member of the Abd-B homeobox family and encodes a protein with a homeobox DNA-binding domain. It is included in a cluster of homeobox D genes located on chromosome 2. The encoded nuclear protein functions as a sequence-specific transcription factor that is expressed in the developing limb buds and is involved in differentiation and l...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Canis lupus familiaris Bos taurus Pan troglodytes Gallus gallus
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
NFAT_Q4_01 TGGAAA_NFAT_Q4_01 PBX1_02 RTAAACA_FREAC2_01 TGIF_01 STAT4_01 GATA1_01 ARNT_01 OCT1_04 FOX_Q2
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 2
2q31.1


Transcripts Names
NM_002148
Protein Names
Q6NT10
P28358



GO Molecular Function

sequence-specific DNA binding | transcription regulatory region DNA binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | nucleic acid binding | chromatin binding | RNA polymerase II regulatory region DNA binding | DNA binding | sequence-specific double-stranded DNA binding | organic cyclic compound binding | transcription regulatory region sequence-specific DNA binding | double-stranded DNA binding | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | RNA polymerase II regulatory region sequence-specific DNA binding | heterocyclic compound binding

GO Biological Process

RNA metabolic process | transcription by RNA polymerase II | limb development | positive regulation of macromolecule biosynthetic process | muscle tissue development | spinal cord motor neuron differentiation | RNA polymerase II transcription factor activity, sequence-specific DNA binding | embryonic appendage morphogenesis | cell differentiation | nervous system development | neurogenesis | generation of neurons | pattern specification process | positive regulation of cellular biosynthetic process | cellular process | cell fate specification | peripheral nervous system development | limb morphogenesis | neuron development | central nervous system neuron differentiation | positive regulation of nitrogen compound metabolic process | tissue development | muscle structure development | skeletal muscle organ development | hindlimb morphogenesis | regulation of cellular process | regulation of metabolic process | organic cyclic compound metabolic process | RNA biosynthetic process | cellular aromatic compound metabolic process | spinal cord motor neuron cell fate specification | embryonic limb morphogenesis | skeletal muscle tissue development | cellular nitrogen compound biosynthetic process | reproduction | embryonic skeletal system development | cellular nitrogen compound metabolic process | positive regulation of RNA biosynthetic process | cellular biosynthetic process | embryo development | anterior/posterior pattern specification | neuron fate commitment | regulation of nucleic acid-templated transcription | system development | ventral spinal cord development | nitrogen compound metabolic process | reproductive process | multicellular organism development | regulation of gene expression | forelimb morphogenesis | nervous system process | positive regulation of cellular metabolic process | animal organ morphogenesis | adult locomotory behavior | regulation of nitrogen compound metabolic process | regulation of transcription by RNA polymerase II | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | fertilization | proximal/distal pattern formation | chordate embryonic development | striated muscle tissue development | regulation of cellular metabolic process | skeletal system morphogenesis | embryo development ending in birth or egg hatching | regulation of RNA metabolic process | single fertilization | embryonic morphogenesis | neuron differentiation | embryonic organ morphogenesis | transcriptional activator activity, RNA polymerase II transcription regulatory region sequence-specific DNA binding | DNA-binding transcription factor activity | regionalization | anatomical structure development | embryonic skeletal system morphogenesis | metabolic process | cell fate commitment | regulation of RNA biosynthetic process | embryonic organ development | peripheral nervous system neuron development | behavior | nucleobase-containing compound metabolic process | organic substance metabolic process | animal organ development | gene expression | transcription, DNA-templated | adult behavior | cell differentiation in spinal cord | regulation of transcription, DNA-templated | neuromuscular process | cell development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | developmental process | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | heterocycle metabolic process | central nervous system development | spinal cord development | positive regulation of metabolic process | skeletal system development | cellular metabolic process | peripheral nervous system neuron differentiation | neuron fate specification | sexual reproduction | muscle organ development | positive regulation of gene expression | macromolecule metabolic process | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | nuclear lumen | ribonucleoprotein granule | cytoplasm | intracellular organelle | protein-containing complex | nucleoplasm | ribonucleoprotein complex | membrane-bounded organelle | nucleus | organelle | cytoplasmic ribonucleoprotein granule | membrane-enclosed lumen | cytosol | intracellular