QuickView for HOXD12;jsessionid=C26DD3BC60C4F30B99833C66D1BC090F (gene)

Gene Symbol:

HOXD12 Homo sapiens

Full name:

homeobox D12

Synonyms:

HOX4H, homeobox protein Hox-D12, Hox-4.7, mouse, homolog of, homeo box D12, homeobox protein Hox-4H

Genomic Location:

Chr 2: 176672776-176673734

Description:

This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arr...

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This gene belongs to the homeobox family of genes. The homeobox genes encode a highly conserved family of transcription factors that play an important role in morphogenesis in all multicellular organisms. Mammals possess four similar homeobox gene clusters, HOXA, HOXB, HOXC and HOXD, located on different chromosomes, consisting of 9 to 11 genes arranged in tandem. This gene is one of several homeobox HOXD genes located in a cluster on chromosome 2. Deletions that remove the entire HOXD gene cluster or the 5' end of this cluster have been associated with severe limb and genital abnormalities. The exact role of this gene has not been determined.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

SMTTTTGT_UNKNOWN ,  RNCTGNYNRNCTGNY_UNKNOWN ,  TAAYNRNNTCC_UNKNOWN ,  PAX8_01 ,  ZIC3_01 ,  CTTTGA_LEF1_Q2 ,  TCF4_Q5 ,  CEBPDELTA_Q6 ,  LEF1_Q6 ,  GGGCGGR_SP1_Q6 ,  CTTTAAR_UNKNOWN ,  PAX8_B ,  PTF1BETA_Q6 ,  GATGKMRGCG_UNKNOWN ,  GATA1_05 ,  TEF_Q6 ,  CDC5_01 ,  ACAWYAAAG_UNKNOWN ,  YAATNANRNNNCAG_UNKNOWN ,  COREBINDINGFACTOR_Q6 ,  GTTRYCATRR_UNKNOWN

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Cytogenetic Map:

2q31.1

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