QuickView for HS3ST3A1 (gene)

Gene Symbol:

HS3ST3A1 Homo sapiens

Full name:

heparan sulfate-glucosamine 3-sulfotransferase 3A1

Synonyms:

3-OST-3A, 3OST3A1, heparan sulfate glucosamine 3-O-sulfotransferase 3A1, heparan sulfate (glucosamine) 3-O-sulfotransferase 3A1, heparan sulfate 3-O-sulfotransferase 3A1, heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3A1, heparin-glucosamine 3-O-sulfotransferase

Genomic Location:

Chr 17: 13339731-13445969

Description:

Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-...

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Heparan sulfate biosynthetic enzymes are key components in generating a myriad of distinct heparan sulfate fine structures that carry out multiple biologic activities. The enzyme encoded by this gene is a member of the heparan sulfate biosynthetic enzyme family. It is a type II integral membrane protein and possesses heparan sulfate glucosaminyl 3-O-sulfotransferase activity. The sulfotransferase domain of this enzyme is highly similar to the same domain of heparan sulfate D-glucosaminyl 3-O-sulfotransferase 3B1, and these two enzymes sulfate an identical disaccharide. This gene is widely expressed, with the most abundant expression in liver and placenta.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Pan troglodytes ,  Canis lupus familiaris ,  Bos taurus ,  Gallus gallus

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

CREBP1CJUN_01 ,  CREB_Q4_01 ,  CACGTG_MYC_Q2 ,  MEIS1BHOXA9_01 ,  CDP_01 ,  TGAYRTCA_ATF3_Q6 ,  ATF_B ,  DBP_Q6 ,  GGGYGTGNY_UNKNOWN ,  GTGACGY_E4F1_Q6 ,  ATF_01 ,  CREB_02 ,  USF_C ,  RNGTGGGC_UNKNOWN ,  MEIS1AHOXA9_01 ,  NMYC_01 ,  ATF1_Q6 ,  CREB_Q2 ,  TGACGTCA_ATF3_Q6 ,  TGACAGNY_MEIS1_01 ,  DR4_Q2 ,  CREB_Q2_01 ,  CREB_01

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Cytogenetic Map:

17p12

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