QuickView for HSC (gene)

Gene Symbol:

FUT1 Homo sapiens

Full name:

fucosyltransferase 1 (H blood group)

Synonyms:

H, HH, HSC, galactoside 2-alpha-L-fucosyltransferase 1, GDP-L-fucose:beta-D-galactoside 2-alpha-L-fucosyltransferase 1, alpha(1,2) fucosyltransferase 1, alpha(1,2)FT 1, blood group H alpha 2-fucosyltransferase, galactoside 2-alpha-L-fucosyltransferase, truncated fucosyltransferase 1

Genomic Location:

Chr 19: 53943080-53950459

Description:

This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.

This gene encodes a Golgi stack membrane protein that is involved in the creation of a precursor of the H antigen, which is required for the final step in the synthesis of soluble A and B antigens. This is one of two genes encoding the galactoside 2-L-fucosyltransferase enzyme. Mutations in this gene are a cause of the H-Bombay blood group.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Pan troglodytes ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

GGGYGTGNY_UNKNOWN ,  GGGCGGR_SP1_Q6

Cytogenetic Map:

19q13.33

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