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QuickView for HSPA1L (gene)


Gene Symbol:
HSPA1L Homo sapiens Homo sapiens
Full name:
heat shock protein family A (Hsp70) member 1 like
Synonyms:
HSP70-1L, HSP70-HOM, HSP70T, hum70t, heat shock 70 kDa protein 1-like, heat shock 10kDa protein 1-like, heat shock 70 kDa protein 1-Hom, heat shock 70 kDa protein 1L, heat shock 70kD protein-like 1, heat shock 70kDa protein 1-like
Genomic Location:
Chr 6: 31885375-31890814
Description:
This gene encodes a 70kDa heat shock protein. In conjunction with other heat shock proteins, this protein stabilizes existing proteins against aggregation and mediates the folding of newly translated proteins in the cytosol and in organelles. The gene is located in the major histocompatibility complex class III region, in a cluster with two closely...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 6
6p21.33





GO Molecular Function

enzyme binding | ribonucleotide binding | nucleotide binding | hydrolase activity | carbohydrate derivative binding | unfolded protein binding | ATPase activity | pyrophosphatase activity | catalytic activity | ATP binding | ubiquitin-like protein ligase binding | anion binding | adenyl nucleotide binding | nucleoside-triphosphatase activity | ATPase activity, coupled | purine nucleotide binding | ion binding | organic cyclic compound binding | protein binding involved in protein folding | purine ribonucleoside triphosphate binding | protein binding | misfolded protein binding | ubiquitin protein ligase binding | hydrolase activity, acting on acid anhydrides | purine ribonucleotide binding | adenyl ribonucleotide binding | drug binding | heat shock protein binding | heterocyclic compound binding | hydrolase activity, acting on acid anhydrides, in phosphorus-containing anhydrides | small molecule binding

GO Biological Process

regulation of intracellular protein transport | positive regulation of cellular component organization | 'de novo' posttranslational protein folding | regulation of cellular localization | regulation of localization | regulation of organelle organization | cellular process | chaperone-mediated protein folding | cell recognition | regulation of cellular process | cellular response to unfolded protein | response to topologically incorrect protein | cellular response to topologically incorrect protein | response to stimulus | regulation of cellular protein localization | regulation of cellular response to heat | positive regulation of protein targeting to mitochondrion | response to stress | positive regulation of cellular protein localization | sperm-egg recognition | reproduction | response to temperature stimulus | regulation of protein transport | regulation of peptide transport | regulation of intracellular transport | positive regulation of mitochondrion organization | regulation of cellular response to stress | reproductive process | positive regulation of organelle organization | binding of sperm to zona pellucida | cellular response to stress | positive regulation of intracellular protein transport | cellular response to heat | cell-cell recognition | 'de novo' protein folding | fertilization | regulation of mitochondrion organization | protein binding involved in protein folding | positive regulation of establishment of protein localization | positive regulation of transport | single fertilization | regulation of establishment of protein localization | response to organic substance | regulation of protein targeting | protein folding | response to heat | positive regulation of intracellular transport | positive regulation of protein transport | response to unfolded protein | chaperone cofactor-dependent protein refolding | regulation of transport | protein refolding | cellular response to organic substance | regulation of protein localization | sexual reproduction | regulation of cellular component organization | regulation of protein targeting to mitochondrion

GO Cellular Component

intracellular membrane-bounded organelle | COP9 signalosome | cell body | cell | nuclear lumen | cytoplasm | intracellular organelle | protein-containing complex | zona pellucida receptor complex | nucleoplasm | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | membrane-enclosed lumen | blood microparticle | cytosol | intracellular