QuickView for Hhex (gene)

Gene Symbol:

HHEX Homo sapiens

Full name:

hematopoietically expressed homeobox

Synonyms:

HEX, HMPH, HOX11L-PEN, PRH, PRHX, hematopoietically-expressed homeobox protein HHEX, homeobox protein HEX, homeobox protein PRH, homeobox, hematopoietically expressed, proline-rich homeodomain-containing transcription factor

Genomic Location:

Chr 10: 94439661-94445388

Description:

This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

This gene encodes a member of the homeobox family of transcription factors, many of which are involved in developmental processes. Expression in specific hematopoietic lineages suggests that this protein may play a role in hematopoietic differentiation.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  D. melanogaster ,  C. elegans ,  Macaca mulatta ,  Danio rerio ,  Gallus gallus ,  Pan troglodytes ,  Bos taurus ,  Canis lupus familiaris

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

PBX1_02 ,  HNF4ALPHA_Q6 ,  STAT4_01 ,  GATA1_01 ,  STAT1_02 ,  RYTTCCTG_ETS2_B ,  CACGTG_MYC_Q2 ,  CATTGTYY_SOX9_B1 ,  STAT6_02 ,  GCANCTGNY_MYOD_Q6 ,  AACTGAC_MIR223 ,  FOXD3_01 ,  AAANWWTGC_UNKNOWN ,  HFH1_01 ,  MAX_01 ,  PEA3_Q6 ,  ATF4_Q2 ,  HP1SITEFACTOR_Q6 ,  VDR_Q6 ,  STAT1_03 ,  NKX22_01 ,  MYB_Q5_01 ,  CREB_Q4 ,  CREBP1_Q2 ,  SOX9_B1 ,  TITF1_Q3 ,  EGR_Q6 ,  SP3_Q3 ,  EVI1_05 ,  CCAWYNNGAAR_UNKNOWN ,  CATRRAGC_UNKNOWN ,  GGGCGGR_SP1_Q6 ,  TGCTGAY_UNKNOWN ,  YKACATTT_UNKNOWN ,  GAANYNYGACNY_UNKNOWN ,  FOXO1_01 ,  SOX5_01 ,  GATA1_02 ,  MYB_Q6 ,  TTGTTT_FOXO4_01 ,  YTAAYNGCT_UNKNOWN ,  CHOP_01 ,  WTTGKCTG_UNKNOWN ,  CREB_Q2 ,  RGAGGAARY_PU1_Q6 ,  SMAD4_Q6 ,  PAX_Q6 ,  EGR1_01 ,  YRCCAKNNGNCGC_UNKNOWN ,  CAGCTG_AP4_Q5 ,  USF2_Q6 ,  PPAR_DR1_Q2 ,  GTTRYCATRR_UNKNOWN ,  GGGTGGRR_PAX4_03 ,  MYB_Q3

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miRNA binding sites
(Source: TargetScan):

Predicted Gene Targets for miR-223

Cytogenetic Map:

10q23.33

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