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QuickView for ID2 (gene)


Gene Symbol:
ID2 Homo sapiens Homo sapiens
Full name:
inhibitor of DNA binding 2
Synonyms:
GIG8, ID2A, ID2H, bHLHb26, DNA-binding protein inhibitor ID-2, DNA-binding protein inhibitor ID2, cell growth-inhibiting gene 8, class B basic helix-loop-helix protein 26, helix-loop-helix protein ID2, inhibitor of DNA binding 2, HLH protein, inhibitor of DNA binding 2, dominant negative helix-loop-helix protein, inhibitor of differentiation 2
Genomic Location:
Chr 2: 8739564-8742034
Description:
The protein encoded by this gene belongs to the inhibitor of DNA binding family, members of which are transcriptional regulators that contain a helix-loop-helix (HLH) domain but not a basic domain. Members of the inhibitor of DNA binding family inhibit the functions of basic helix-loop-helix transcription factors in a dominant-negative manner by su...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Danio rerio Gallus gallus Bos taurus Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
miRNA binding sites
(Source: TargetScan):
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 2
2p25.1


Transcripts Names
NM_002166
Protein Names
Q02363
Q53T66



GO Molecular Function

transcription factor activity, transcription factor binding | RNA polymerase II transcription factor activity, sequence-specific DNA binding | transcription factor activity, RNA polymerase II transcription factor binding | transcriptional repressor activity, RNA polymerase II transcription factor binding | ion channel binding | protein binding | DNA-binding transcription factor activity | transcription factor binding | RNA polymerase II transcription factor binding | protein dimerization activity

GO Biological Process

negative regulation of lymphocyte differentiation | RNA metabolic process | negative regulation of leukocyte activation | positive regulation of smooth muscle cell proliferation | positive regulation of erythrocyte differentiation | adipose tissue development | brain development | response to radiation | cell morphogenesis | bundle of His development | endodermal digestive tract morphogenesis | regulation of cell cycle process | transcription factor activity, transcription factor binding | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | mucosal-associated lymphoid tissue development | regulation of B cell activation | regulation of neurogenesis | muscle tissue development | regulation of cell development | regulation of cell cycle G1/S phase transition | erythrocyte homeostasis | regulation of immune system process | myeloid cell differentiation | negative regulation of cellular process | RNA polymerase II transcription factor activity, sequence-specific DNA binding | positive regulation of developmental process | negative regulation of RNA biosynthetic process | response to metal ion | cell differentiation | nervous system development | regulation of G1/S transition of mitotic cell cycle | neurogenesis | generation of neurons | enucleate erythrocyte differentiation | positive regulation of cellular biosynthetic process | cellular process | negative regulation of gliogenesis | lymphocyte differentiation | circadian regulation of gene expression | cell maturation | heart morphogenesis | neuron development | immune system development | negative regulation of nucleic acid-templated transcription | digestive tract morphogenesis | regulation of cell cycle | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | transcription factor activity, RNA polymerase II transcription factor binding | response to inorganic substance | negative regulation of cellular metabolic process | tissue development | regulation of binding | regulation of fat cell differentiation | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | ventricular septum morphogenesis | regulation of cellular process | leukocyte activation | regulation of osteoblast differentiation | regulation of metabolic process | gliogenesis | organic cyclic compound metabolic process | RNA biosynthetic process | epithelium development | cellular aromatic compound metabolic process | positive regulation of transcription involved in G1/S transition of mitotic cell cycle | cellular component organization | cellular response to metal ion | urogenital system development | head development | epithelial cell differentiation involved in mammary gland alveolus development | response to stimulus | cellular response to lithium ion | positive regulation of blood pressure | cell morphogenesis involved in neuron differentiation | regulation of mitotic cell cycle phase transition | oligodendrocyte development | natural killer cell differentiation | positive regulation of immune system process | transcriptional repressor activity, RNA polymerase II transcription factor binding | response to stress | negative regulation of lymphocyte activation | cellular nitrogen compound biosynthetic process | regulation of cell proliferation | tube morphogenesis | cardiac muscle tissue development | regulation of cell cycle phase transition | circadian rhythm | cellular response to inorganic substance | embryonic digestive tract morphogenesis | rhythmic process | cellular nitrogen compound metabolic process | cell cycle G1/S phase transition | regulation of DNA binding | positive regulation of gliogenesis | blood circulation | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | hemopoiesis | negative regulation of hemopoiesis | cellular biosynthetic process | kidney development | embryo development | regulation of oligodendrocyte differentiation | regulation of lymphocyte differentiation | myeloid cell homeostasis | neuron fate commitment | positive regulation of macrophage differentiation | regulation of nucleic acid-templated transcription | leukocyte differentiation | locomotion | negative regulation of osteoblast differentiation | response to light stimulus | system development | nitrogen compound metabolic process | multicellular organism development | thigmotaxis | mammary gland development | regulation of ossification | embryonic digestive tract development | telencephalon development | positive regulation of cell cycle | mammary gland lobule development | regulation of neuron differentiation | regulation of gene expression | rhythmic behavior | cellular response to stress | cell cycle | regulation of blood pressure | regulation of cell cycle arrest | positive regulation of cellular metabolic process | regulation of lymphocyte activation | animal organ morphogenesis | adult locomotory behavior | cardiac conduction system development | regulation of nitrogen compound metabolic process | olfactory lobe development | negative regulation of DNA-binding transcription factor activity | negative regulation of DNA binding | regulation of transcription by RNA polymerase II | response to lithium ion | negative regulation of binding | negative regulation of B cell differentiation | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | homeostasis of number of cells | cell proliferation | biosynthetic process | locomotory behavior | aromatic compound biosynthetic process | glial cell differentiation | cardiac septum morphogenesis | digestive tract development | mammary gland epithelial cell proliferation | mitotic cell cycle phase transition | cell morphogenesis involved in differentiation | striated muscle tissue development | regulation of cellular metabolic process | olfactory bulb development | metanephros development | negative regulation of cell activation | regulation of transcription involved in G1/S transition of mitotic cell cycle | heart development | homeostatic process | G1/S transition of mitotic cell cycle | positive regulation of cell proliferation | regulation of RNA metabolic process | renal system development | cell aging | embryonic morphogenesis | negative regulation of B cell activation | regulation of mitotic cell cycle | lymphocyte activation | positive regulation of cell cycle arrest | neuron differentiation | embryonic organ morphogenesis | ventricular septum development | DNA-binding transcription factor activity | cardiac ventricle development | gland development | digestive system development | regulation of hemopoiesis | epithelial cell proliferation | negative regulation of ossification | regulation of DNA-binding transcription factor activity | ventricular cardiac muscle tissue development | anatomical structure development | mitotic cell cycle | positive regulation of neurogenesis | entrainment of circadian clock | regulation of neural precursor cell proliferation | metabolic process | positive regulation of cell development | cell fate commitment | regulation of RNA biosynthetic process | developmental maturation | negative regulation of transcription, DNA-templated | embryonic organ development | regulation of erythrocyte differentiation | oligodendrocyte differentiation | positive regulation of glial cell differentiation | behavior | nucleobase-containing compound metabolic process | organic substance metabolic process | regulation of B cell differentiation | connective tissue development | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | forebrain development | negative regulation of neuron differentiation | gene expression | regulation of cell activation | mammary gland epithelium development | positive regulation of astrocyte differentiation | transcription, DNA-templated | cell activation | mammary gland alveolus development | adult behavior | regulation of glial cell differentiation | regulation of gliogenesis | regulation of macrophage differentiation | negative regulation of molecular function | cellular senescence | natural killer cell activation | regulation of transcription, DNA-templated | glial cell development | cell development | anatomical structure morphogenesis | cellular macromolecule biosynthetic process | positive regulation of fat cell differentiation | Peyer's patch development | regulation of circadian rhythm | regulation of nervous system development | regulation of developmental process | developmental process | erythrocyte differentiation | positive regulation of cell cycle process | negative regulation of glial cell differentiation | cardiac septum development | negative regulation of transcription by RNA polymerase II | tube development | positive regulation of transcription, DNA-templated | membranous septum morphogenesis | negative regulation of cell proliferation | negative regulation of neural precursor cell proliferation | circadian behavior | positive regulation of nucleic acid-templated transcription | entrainment of circadian clock by photoperiod | cell cycle phase transition | epithelial cell differentiation | photoperiodism | cardiac chamber development | heterocycle metabolic process | mammary gland epithelial cell differentiation | central nervous system development | regulation of lipid metabolic process | positive regulation of metabolic process | locomotor rhythm | positive regulation of myeloid leukocyte differentiation | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | regulation of astrocyte differentiation | regulation of smooth muscle cell proliferation | negative regulation of oligodendrocyte differentiation | negative regulation of cell development | circulatory system development | aging | negative regulation of cell differentiation | positive regulation of gene expression | macromolecule metabolic process | negative regulation of neurogenesis | multicellular organismal process

GO Cellular Component

intracellular membrane-bounded organelle | cell | cytoplasm | intracellular organelle | protein-containing complex | membrane-bounded organelle | nucleus | organelle | cytosol | intracellular