QuickView for IGF-IR (gene)

GO Molecular Function

phosphatidylinositol 3-kinase binding | endopeptidase inhibitor activity | transmembrane receptor protein tyrosine kinase activity | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | transmembrane signaling receptor activity | ribonucleotide binding | nucleotide binding | enzyme inhibitor activity | carbohydrate derivative binding | growth factor binding | molecular function regulator | catalytic activity | ATP binding | insulin-like growth factor binding | anion binding | adenyl nucleotide binding | signaling receptor activity | purine nucleotide binding | ion binding | organic cyclic compound binding | purine ribonucleoside triphosphate binding | protein tyrosine kinase activity | protein binding | transferase activity, transferring phosphorus-containing groups | insulin-activated receptor activity | phosphotransferase activity, alcohol group as acceptor | protein kinase activity | transferase activity | cysteine-type endopeptidase regulator activity involved in apoptotic process | purine ribonucleotide binding | peptidase inhibitor activity | enzyme regulator activity | adenyl ribonucleotide binding | drug binding | kinase activity | insulin receptor substrate binding | heterocyclic compound binding | cysteine-type endopeptidase inhibitor activity | small molecule binding | protein-hormone receptor activity

GO Biological Process

semicircular canal development | regulation of ERK1 and ERK2 cascade | inner ear morphogenesis | regulation of cysteine-type endopeptidase activity | endopeptidase inhibitor activity | cell motility | regulation of programmed cell death | peptidyl-amino acid modification | transmembrane receptor protein tyrosine kinase activity | cysteine-type endopeptidase inhibitor activity involved in apoptotic process | eye development | negative regulation of cysteine-type endopeptidase activity | spinal cord motor neuron differentiation | response to hormone | negative regulation of cellular process | cell differentiation | nervous system development | neurogenesis | glucose homeostasis | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | generation of neurons | negative regulation of proteolysis | cellular process | localization | heart morphogenesis | negative regulation of signaling | developmental growth | central nervous system neuron differentiation | multicellular organismal reproductive process | negative regulation of apoptotic process | regulation of proteolysis | positive regulation of nitrogen compound metabolic process | negative regulation of cellular metabolic process | response to peptide hormone | tissue development | gamete generation | regeneration | regulation of cellular process | regulation of apoptotic process | regulation of metabolic process | positive regulation of cellular protein metabolic process | cellular response to organonitrogen compound | insulin-like growth factor receptor signaling pathway | response to stimulus | enzyme inhibitor activity | positive regulation of protein metabolic process | response to stress | fin regeneration | tube morphogenesis | response to peptide | programmed cell death | reproduction | negative regulation of metabolic process | protein modification process | embryo development | macromolecule modification | molecular function regulator | locomotion | response to nitrogen compound | apoptotic process | cellular response to hormone stimulus | system development | ventral spinal cord development | nitrogen compound metabolic process | reproductive process | regulation of signal transduction | semicircular canal morphogenesis | multicellular organism development | negative regulation of catalytic activity | cell migration | cellular response to peptide hormone stimulus | regulation of peptidase activity | regulation of MAPK cascade | phosphorus metabolic process | cellular response to insulin stimulus | regulation of catalytic activity | regulation of phosphorylation | negative regulation of peptidase activity | wound healing | cellular response to peptide | insulin receptor signaling pathway | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | animal organ morphogenesis | protein autophosphorylation | regulation of nitrogen compound metabolic process | enzyme linked receptor protein signaling pathway | regulation of cysteine-type endopeptidase activity involved in apoptotic process | positive regulation of intracellular signal transduction | negative regulation of cysteine-type endopeptidase activity involved in apoptotic process | embryonic camera-type eye development | regulation of cellular protein metabolic process | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | sensory organ development | chordate embryonic development | cell communication | regulation of cellular metabolic process | regulation of protein metabolic process | positive regulation of signal transduction | inner ear development | heart development | homeostatic process | regulation of protein phosphorylation | embryo development ending in birth or egg hatching | embryonic morphogenesis | protein tyrosine kinase activity | neuron differentiation | multicellular organism reproduction | embryonic organ morphogenesis | protein metabolic process | positive regulation of protein modification process | response to organic substance | response to wounding | regulation of intracellular signal transduction | response to insulin | anatomical structure development | cell surface receptor signaling pathway | metabolic process | insulin-activated receptor activity | negative regulation of programmed cell death | embryonic organ development | ear development | chemical homeostasis | protein kinase activity | organic substance metabolic process | cell death | animal organ development | negative regulation of cellular protein metabolic process | positive regulation of ERK1 and ERK2 cascade | regulation of phosphate metabolic process | positive regulation of MAPK cascade | camera-type eye development | negative regulation of protein metabolic process | cell differentiation in spinal cord | regulation of cell communication | cysteine-type endopeptidase regulator activity involved in apoptotic process | negative regulation of molecular function | negative regulation of signal transduction | signaling | positive regulation of phosphorylation | peptidase inhibitor activity | cellular protein metabolic process | enzyme regulator activity | anatomical structure morphogenesis | regulation of endopeptidase activity | germ cell migration | kinase activity | developmental process | cellular protein modification process | tube development | response to organonitrogen compound | negative regulation of hydrolase activity | central nervous system development | spinal cord development | transmembrane receptor protein tyrosine kinase signaling pathway | positive regulation of metabolic process | cellular metabolic process | cellular response to organic substance | regulation of cell death | cysteine-type endopeptidase inhibitor activity | negative regulation of cell death | circulatory system development | carbohydrate homeostasis | ear morphogenesis | tissue regeneration | sexual reproduction | positive regulation of signaling | signal transduction | regulation of signaling | negative regulation of endopeptidase activity | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

integral component of membrane | catalytic complex | neuron projection | protein kinase complex | cell | plasma membrane protein complex | intrinsic component of membrane | cytoplasm | receptor complex | protein-containing complex | cell projection | plasma membrane | transferase complex | integral component of plasma membrane | insulin receptor complex | cell periphery | axon | intracellular | membrane | intrinsic component of plasma membrane

PATHWAYS

No pathways found.

PROTEIN FAMILY

Protein kinase domain | Serine-threonine/tyrosine-protein kinase, catalytic domain | Tyrosine-protein kinase, receptor class II, conserved site | Tyrosine-protein kinase, active site | Protein kinase-like domain superfamily | Protein kinase, ATP binding site | Tyrosine-protein kinase, catalytic domain | Fibronectin type III | Immunoglobulin-like fold | Fibronectin type III superfamily