QuickView for IGF2 (gene)

Gene Symbol:

IGF2 Homo sapiens

Full name:

insulin like growth factor 2

Synonyms:

C11orf43, GRDF, IGF-II, PP9974, insulin-like growth factor II, T3M-11-derived growth factor, insulin-like growth factor 2 (somatomedin A), insulin-like growth factor type 2, preptin

Genomic Location:

Chr 11: 2106923-2127409

Description:

This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-thro...

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This gene encodes a member of the insulin family of polypeptide growth factors, which are involved in development and growth. It is an imprinted gene, expressed only from the paternal allele, and epigenetic changes at this locus are associated with Wilms tumour, Beckwith-Wiedemann syndrome, rhabdomyosarcoma, and Silver-Russell syndrome. A read-through INS-IGF2 gene exists, whose 5' region overlaps the INS gene and the 3' region overlaps this gene. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.

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Orthologs:

Mus musculus ,  Rattus norvegicus ,  Macaca mulatta ,  Bos taurus ,  Danio rerio ,  Gallus gallus ,  Canis lupus familiaris ,  Pan troglodytes

External Links:

Entrez Gene

Transcription Factor
Binding Sites:

E12_Q6 ,  MYOD_Q6_01 ,  PBX1_02 ,  GATA1_03 ,  ATGTCAC_MIR489 ,  E2A_Q2 ,  GGGAGGRR_MAZ_Q6 ,  CAGGTG_E12_Q6 ,  MYOD_Q6 ,  GGGCGGR_SP1_Q6 ,  AREB6_03 ,  GGGTGGRR_PAX4_03 ,  LMO2COM_01

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Cytogenetic Map:

11p15.5

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