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QuickView for IGF2BP1 (gene)


Gene Symbol:
IGF2BP1 Homo sapiens Homo sapiens
Full name:
insulin like growth factor 2 mRNA binding protein 1
Synonyms:
CRD-BP, CRDBP, IMP-1, IMP1, VICKZ1, ZBP1, insulin-like growth factor 2 mRNA-binding protein 1, IGF-II mRNA-binding protein 1, IGF2 mRNA-binding protein 1, VICKZ family member 1, ZBP-1, coding region determinant-binding protein, insulin-like growth factor 2 mRNA binding protein 1 deltaN CRDBP, zipcode-binding protein 1
Genomic Location:
Chr 17: 44429773-44488506
Description:
This gene encodes a member of the insulin-like growth factor 2 mRNA-binding protein family. The protein encoded by this gene contains four K homology domains and two RNA recognition motifs. It functions by binding to the mRNAs of certain genes, including insulin-like growth factor 2, beta-actin and beta-transducin repeat-containing protein, and reg...
Orthologs:
Mus musculus Rattus norvegicus D. melanogaster Macaca mulatta Gallus gallus Pan troglodytes Canis lupus familiaris Bos taurus Danio rerio
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
E12_Q6 GATTGGY_NFY_Q6_01 MYOD_Q6_01 TTTGCAG_MIR518A2 AAGCCAT_MIR135A_MIR135B USF_Q6 CCCAGAG_MIR326 RYTTCCTG_ETS2_B ARNT_01 MYCMAX_03
miRNA binding sites
(Source: miRecords):
Cytogenetic Map:
chr 17
17q21.32





GO Molecular Function

nucleic acid binding | mRNA binding | organic cyclic compound binding | protein binding | translation regulator activity | mRNA 5'-UTR binding | mRNA 3'-UTR binding | heterocyclic compound binding | RNA binding

GO Biological Process

brain development | RNA stabilization | establishment of localization | negative regulation of cellular process | mRNA stabilization | nervous system development | cellular process | regulation of cytokine biosynthetic process | localization | stem cell population maintenance | macromolecule localization | negative regulation of cellular metabolic process | regulation of mRNA stability | regulation of cellular process | regulation of metabolic process | head development | response to stimulus | response to stress | posttranscriptional regulation of gene expression | negative regulation of metabolic process | regulation of mRNA stability involved in response to stress | system development | pallium cell proliferation in forebrain | multicellular organism development | telencephalon development | regulation of gene expression | organic substance transport | cellular response to stress | regulation of nitrogen compound metabolic process | regulation of RNA stability | cell proliferation | regulation of cellular protein metabolic process | mRNA transport | establishment of RNA localization | regulation of cellular metabolic process | regulation of protein metabolic process | regulation of RNA metabolic process | neuronal stem cell population maintenance | cell proliferation in forebrain | negative regulation of mRNA catabolic process | translation regulator activity | anatomical structure development | nucleobase-containing compound transport | maintenance of cell number | negative regulation of biosynthetic process | negative regulation of gene expression | animal organ development | regulation of mRNA catabolic process | forebrain development | pallium development | negative regulation of cellular protein metabolic process | neural precursor cell proliferation | negative regulation of translation | RNA transport | negative regulation of protein metabolic process | regulation of cytokine production | developmental process | CRD-mediated mRNA stabilization | central nervous system development | positive regulation of metabolic process | regulation of translation | RNA localization | positive regulation of gene expression | multicellular organismal process

GO Cellular Component

dendritic spine | dendrite | intracellular membrane-bounded organelle | synapse | neuron projection | somatodendritic compartment | cytoplasmic stress granule | CRD-mediated mRNA stability complex | actin-based cell projection | cell | nuclear lumen | distal axon | ribonucleoprotein granule | lamellipodium | cytoplasm | intracellular organelle | dendritic tree | protein-containing complex | cell projection | neuron spine | postsynapse | nucleoplasm | cell leading edge | ribonucleoprotein complex | perinuclear region of cytoplasm | site of polarized growth | membrane-bounded organelle | filopodium | nucleus | organelle | cytoplasmic ribonucleoprotein granule | axon | membrane-enclosed lumen | growth cone | cytosol | intracellular