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QuickView for IL-15 (gene)


Gene Symbol:
IL15 Homo sapiens Homo sapiens
Full name:
interleukin 15
Synonyms:
IL-15, interleukin-15
Genomic Location:
Chr 4: 142777204-142874062
Description:
The protein encoded by this gene is a cytokine that regulates T and natural killer cell activation and proliferation. This cytokine and interleukine 2 share many biological activities. They are found to bind common hematopoietin receptor subunits, and may compete for the same receptor, and thus negatively regulate each other's activity. The number ...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Gallus gallus Canis lupus familiaris Pan troglodytes
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 4
4q31.21





GO Molecular Function

signaling receptor binding | cytokine receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity

GO Biological Process

positive regulation of immune response | response to extracellular stimulus | positive regulation of macromolecule biosynthetic process | response to nutrient levels | response to cytokine | intracellular signal transduction | positive regulation of peptidyl-tyrosine phosphorylation | peptidyl-amino acid modification | regulation of immune system process | negative regulation of cellular process | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | regulation of T cell differentiation | JAK-STAT cascade | defense response | cellular response to extracellular stimulus | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | peptidyl-tyrosine phosphorylation | striated muscle atrophy | positive regulation of cellular biosynthetic process | cellular process | positive regulation of glycoprotein biosynthetic process | lymphocyte differentiation | cell maturation | immune system development | regulation of defense response to virus | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | positive regulation of natural killer cell proliferation | regulation of cell differentiation | regulation of immune response | regulation of cellular process | leukocyte activation | cellular response to lipid | regulation of metabolic process | alpha-beta T cell proliferation | positive regulation of cellular protein metabolic process | regulation of natural killer cell activation | T cell activation | positive regulation of interleukin-17 production | response to stimulus | regulation of glycoprotein biosynthetic process | regulation of peptidyl-tyrosine phosphorylation | natural killer cell differentiation | positive regulation of immune system process | positive regulation of protein metabolic process | mononuclear cell proliferation | response to stress | positive regulation of JAK-STAT cascade | cellular response to vitamin | positive regulation of lymphocyte proliferation | regulation of cell proliferation | positive regulation of cell-cell adhesion | positive regulation of cell activation | positive regulation of natural killer cell activation | positive regulation of T cell activation | cellular response to organic cyclic compound | response to vitamin D | negative regulation of metabolic process | hemopoiesis | protein modification process | regulation of cell adhesion | macromolecule modification | cell-cell signaling | molecular function regulator | regulation of lymphocyte differentiation | leukocyte differentiation | positive regulation of natural killer cell differentiation | positive regulation of mononuclear cell proliferation | system development | cellular response to nutrient levels | cellular response to vitamin D | nitrogen compound metabolic process | regulation of signal transduction | multicellular organism development | positive regulation of lymphocyte differentiation | phosphorus metabolic process | positive regulation of inflammatory response | negative regulation of cold-induced thermogenesis | regulation of phosphorylation | hyaluronan metabolic process | regulation of T cell activation | response to lipid | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | negative regulation of smooth muscle cell proliferation | regulation of nitrogen compound metabolic process | small molecule metabolic process | positive regulation of STAT cascade | cytokine-mediated signaling pathway | positive regulation of intracellular signal transduction | positive regulation of protein O-linked glycosylation | response to nutrient | positive regulation of cell differentiation | NK T cell proliferation | cellular response to cytokine stimulus | cell proliferation | leukocyte proliferation | regulation of cellular protein metabolic process | positive regulation of T cell proliferation | extrathymic T cell selection | phosphorylation | protein phosphorylation | phosphate-containing compound metabolic process | cell communication | regulation of cellular metabolic process | regulation of natural killer cell proliferation | skeletal muscle atrophy | positive regulation of tyrosine phosphorylation of STAT protein | inflammatory response | regulation of protein metabolic process | positive regulation of signal transduction | positive regulation of cell proliferation | regulation of protein phosphorylation | carboxylic acid metabolic process | lymphocyte activation | lymph node development | interleukin-15-mediated signaling pathway | T cell differentiation | regulation of signaling receptor activity | receptor regulator activity | response to interleukin-15 | protein metabolic process | cellular response to nutrient | skeletal muscle adaptation | positive regulation of protein modification process | T cell selection | response to organic substance | regulation of hemopoiesis | positive regulation of protein glycosylation | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | metabolic process | positive regulation of leukocyte activation | developmental maturation | regulation of tissue remodeling | receptor ligand activity | immune response | cytokine activity | organic substance metabolic process | response to vitamin | animal organ development | T cell proliferation | regulation of cell activation | muscle atrophy | alpha-beta T cell activation | regulation of phosphate metabolic process | positive regulation of glycoprotein metabolic process | positive regulation of cytokine production | cell activation | NK T cell activation | regulation of natural killer cell differentiation | lymphocyte proliferation | regulation of cell communication | natural killer cell activation | signaling | response to organic cyclic compound | cell development | regulation of T cell proliferation | organic acid metabolic process | positive regulation of phosphorylation | cellular protein metabolic process | regulation of cytokine production | positive regulation of tissue remodeling | tyrosine phosphorylation of STAT protein | regulation of developmental process | developmental process | cellular protein modification process | carbohydrate derivative metabolic process | negative regulation of cell proliferation | regulation of cell-cell adhesion | regulation of defense response to virus by host | positive regulation of metabolic process | immune system process | cellular metabolic process | hematopoietic or lymphoid organ development | cellular response to organic substance | regulation of smooth muscle cell proliferation | regulation of inflammatory response | aging | regulation of protein glycosylation | positive regulation of leukocyte cell-cell adhesion | muscle system process | positive regulation of signaling | signal transduction | regulation of signaling | glycosaminoglycan metabolic process | macromolecule metabolic process | multicellular organismal process | regulation of phosphorus metabolic process

GO Cellular Component

intracellular membrane-bounded organelle | cytoplasmic vesicle | cell | nuclear lumen | cytoplasm | intracellular organelle | nuclear body | Golgi apparatus | endomembrane system | nucleoplasm | nuclear speck | vesicle | endosome | extracellular region | membrane-bounded organelle | nucleus | organelle | extracellular space | membrane-enclosed lumen | cytosol | intracellular vesicle | cell surface | intracellular