Correlation Engine 2.0
Clear Search sequence regions
Bookmark Forward Export SNPs

QuickView for IL-17A (gene)


Gene Symbol:
IL17A Homo sapiens Homo sapiens
Full name:
interleukin 17A
Synonyms:
CTLA-8, CTLA8, IL-17, IL-17A, IL17, interleukin-17A, cytotoxic T-lymphocyte-associated antigen 8, cytotoxic T-lymphocyte-associated protein 8, interleukin 17 (cytotoxic T-lymphocyte-associated serine esterase 8)
Genomic Location:
Chr 6: 52159144-52163395
Description:
The protein encoded by this gene is a proinflammatory cytokine produced by activated T cells. This cytokine regulates the activities of NF-kappaB and mitogen-activated protein kinases. This cytokine can stimulate the expression of IL6 and cyclooxygenase-2 (PTGS2/COX-2), as well as enhance the production of nitric oxide (NO). High levels of this cyt...
Orthologs:
Mus musculus Rattus norvegicus Macaca mulatta Bos taurus Pan troglodytes Canis lupus familiaris
External Links:
Entrez Gene
Transcription Factor
Binding Sites:
Cytogenetic Map:
chr 6
6p12.2


Transcripts Names
NM_002190
Protein Names
Q16552
Q5T2P0



GO Molecular Function

signaling receptor binding | molecular function regulator | protein binding | receptor regulator activity | receptor ligand activity | cytokine activity

GO Biological Process

positive regulation of macromolecule biosynthetic process | response to cytokine | response to interleukin-1 | regulation of localization | defense response to other organism | regulation of immune system process | positive regulation of developmental process | defense response | positive regulation of protein secretion | positive regulation of cellular biosynthetic process | cellular process | regulation of myeloid cell differentiation | positive regulation of nitrogen compound metabolic process | regulation of myeloid leukocyte differentiation | regulation of cell differentiation | regulation of cellular process | regulation of metabolic process | interleukin-17-mediated signaling pathway | regulation of peptide secretion | response to stimulus | defense response to fungus | positive regulation of osteoclast differentiation | positive regulation of immune system process | response to stress | programmed cell death | positive regulation of cytokine secretion | regulation of protein transport | positive regulation of RNA biosynthetic process | regulation of peptide transport | cell-cell signaling | molecular function regulator | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | apoptotic process | response to external biotic stimulus | regulation of signal transduction | positive regulation of inflammatory response | regulation of gene expression | positive regulation of secretion | positive regulation of cellular metabolic process | regulation of nitrogen compound metabolic process | cytokine-mediated signaling pathway | regulation of transcription by RNA polymerase II | positive regulation of cytokine production involved in inflammatory response | positive regulation of cell differentiation | positive regulation of myeloid cell differentiation | cellular response to cytokine stimulus | regulation of cytokine production involved in inflammatory response | positive regulation of interleukin-23 production | regulation of interleukin-23 production | response to fungus | cell communication | regulation of cellular metabolic process | inflammatory response | positive regulation of establishment of protein localization | regulation of RNA metabolic process | positive regulation of transport | regulation of cytokine secretion | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | response to organic substance | regulation of hemopoiesis | cell surface receptor signaling pathway | regulation of RNA biosynthetic process | regulation of secretion | receptor ligand activity | positive regulation of interleukin-6 production | immune response | cytokine activity | cell death | regulation of protein secretion | positive regulation of cytokine production | cell activation | fibroblast activation | positive regulation of protein transport | regulation of osteoclast differentiation | regulation of cell communication | signaling | regulation of transcription, DNA-templated | regulation of cytokine production | response to biotic stimulus | regulation of developmental process | cellular response to interleukin-1 | regulation of transport | positive regulation of transcription, DNA-templated | positive regulation of nucleic acid-templated transcription | positive regulation of transcription by RNA polymerase II | positive regulation of metabolic process | positive regulation of myeloid leukocyte differentiation | immune system process | cellular response to organic substance | regulation of protein localization | regulation of interleukin-6 production | regulation of inflammatory response | response to other organism | signal transduction | regulation of signaling | positive regulation of gene expression | positive regulation of interleukin-6 secretion

GO Cellular Component

cell | external side of plasma membrane | plasma membrane | extracellular region | extracellular space | cell periphery | cell surface | membrane