QuickView for IL-2 (gene)
- Gene Symbol:
- Il2
Mus musculus - Full name:
- interleukin 2
- Synonyms:
- Il-2, interleukin-2, T-cell growth factor, TCGF
- Genomic Location:
- Chr 3: 37019644-37024875
- Orthologs:
- Homo sapiens , Rattus norvegicus , Macaca mulatta , Bos taurus , Canis lupus familiaris , Pan troglodytes
- External Links:
- Entrez Gene
- Transcription Factor
Binding Sites:
- miRNA binding sites
(Source: TargetScan):
GO Molecular Function
opioid receptor binding | lipid binding | signaling receptor binding | carbohydrate derivative binding | cytokine receptor binding | molecular function regulator | glycolipid binding | sphingolipid binding | carbohydrate binding | protein binding | receptor regulator activity | glycosphingolipid binding | growth factor activity | kappa-type opioid receptor binding | G-protein coupled receptor binding | receptor ligand activity | cytokine activity | growth factor receptor binding | interleukin-2 receptor binding
GO Biological Process
positive regulation of immune response | negative regulation of lymphocyte differentiation | negative regulation of leukocyte activation | negative regulation of phosphorylation | adaptive immune response | positive regulation of macromolecule biosynthetic process | negative regulation of immune system process | positive regulation of cellular component organization | regulation of B cell activation | regulation of neurogenesis | regulation of cell development | regulation of localization | regulation of programmed cell death | positive regulation of peptidyl-tyrosine phosphorylation | regulation of immune system process | regulation of T-helper 17 type immune response | negative regulation of cellular process | negative regulation of leukocyte cell-cell adhesion | positive regulation of developmental process | positive regulation of lymphocyte activation | cell differentiation | regulation of T cell differentiation | nervous system development | response to drug | negative regulation of protein phosphorylation | cellular chemical homeostasis | positive regulation of DNA recombination | neurogenesis | positive regulation of cell adhesion | positive regulation of phosphate metabolic process | generation of neurons | positive regulation of protein secretion | response to antibiotic | regulation of isotype switching to IgG isotypes | positive regulation of T cell differentiation | positive regulation of cellular biosynthetic process | regulation of immunoglobulin secretion | cellular process | negative regulation of inflammatory response | cellular homeostasis | extrinsic apoptotic signaling pathway | positive regulation of immune effector process | positive regulation of adaptive immune response | negative regulation of alpha-beta T cell differentiation | negative regulation of apoptotic process | negative regulation of T-helper 17 cell differentiation | regulation of tyrosine phosphorylation of STAT protein | positive regulation of nitrogen compound metabolic process | regulation of neuron projection development | negative regulation of cellular metabolic process | regulation of cell differentiation | negative regulation of CD4-positive, alpha-beta T cell activation | regulation of lymphocyte apoptotic process | regulation of immune response | regulation of cellular process | leukocyte activation | regulation of apoptotic process | regulation of metabolic process | positive regulation of activated T cell proliferation | regulation of cytosolic calcium ion concentration | negative regulation of mononuclear cell proliferation | positive regulation of interferon-gamma production | positive regulation of cellular protein metabolic process | calcium ion homeostasis | positive regulation of interleukin-17 production | regulation of peptide secretion | response to stimulus | regulation of DNA recombination | regulation of regulatory T cell differentiation | regulation of peptidyl-tyrosine phosphorylation | positive regulation of immune system process | positive regulation of protein metabolic process | negative regulation of cell adhesion | regulation of CD4-positive, alpha-beta T cell activation | positive regulation of immunoglobulin production | positive regulation of JAK-STAT cascade | negative regulation of lymphocyte activation | leukocyte activation involved in immune response | positive regulation of lymphocyte proliferation | regulation of cell proliferation | regulation of blood circulation | positive regulation of cell-cell adhesion | positive regulation of B cell proliferation | programmed cell death | positive regulation of cell activation | response to alcohol | positive regulation of T cell activation | regulation of protein transport | G-protein coupled receptor signaling pathway | negative regulation of metabolic process | positive regulation of RNA biosynthetic process | negative regulation of hemopoiesis | regulation of peptide transport | regulation of cell adhesion | molecular function regulator | metal ion homeostasis | regulation of lymphocyte differentiation | negative regulation of adaptive immune response | response to ethanol | regulation of nucleic acid-templated transcription | positive regulation of peptide secretion | apoptotic process | positive regulation of mononuclear cell proliferation | system development | regulation of signal transduction | negative regulation of T-helper cell differentiation | negative regulation of phosphate metabolic process | positive regulation of neuron projection development | multicellular organism development | positive regulation of lymphocyte differentiation | regulation of phosphorylation | regulation of CD4-positive, alpha-beta T cell differentiation | regulation of T cell activation | regulation of activated T cell proliferation | regulation of neuron differentiation | regulation of gene expression | positive regulation of secretion | negative regulation of T-helper 17 type immune response | positive regulation of cellular metabolic process | positive regulation of protein phosphorylation | regulation of lymphocyte activation | cellular ion homeostasis | regulation of T cell homeostatic proliferation | negative regulation of lymphocyte apoptotic process | positive regulation of cytosolic calcium ion concentration | regulation of nitrogen compound metabolic process | negative regulation of T cell activation | positive regulation of cell projection organization | positive regulation of STAT cascade | positive regulation of intracellular signal transduction | regulation of transcription by RNA polymerase II | regulation of T-helper 17 cell differentiation | positive regulation of cell differentiation | negative regulation of B cell apoptotic process | regulation of cellular protein metabolic process | positive regulation of immunoglobulin mediated immune response | positive regulation of T cell proliferation | negative regulation of immune response | response to toxic substance | positive regulation of dendritic spine development | regulation of heart contraction | positive regulation of isotype switching | cation homeostasis | regulation of B cell apoptotic process | negative regulation of cell-cell adhesion | cellular cation homeostasis | cell communication | regulation of cellular metabolic process | positive regulation of tyrosine phosphorylation of STAT protein | regulation of alpha-beta T cell differentiation | negative regulation of cell activation | cell activation involved in immune response | regulation of protein metabolic process | positive regulation of signal transduction | cellular calcium ion homeostasis | homeostatic process | positive regulation of cell proliferation | positive regulation of establishment of protein localization | regulation of protein phosphorylation | protein kinase C-activating G-protein coupled receptor signaling pathway | negative regulation of CD4-positive, alpha-beta T cell differentiation | regulation of RNA metabolic process | positive regulation of B cell activation | positive regulation of transport | apoptotic signaling pathway | negative regulation of T cell differentiation | positive regulation of dendrite development | regulation of signaling receptor activity | receptor regulator activity | regulation of establishment of protein localization | positive regulation of protein modification process | response to organic substance | regulation of hemopoiesis | regulation of JAK-STAT cascade | regulation of intracellular signal transduction | anatomical structure development | cell surface receptor signaling pathway | positive regulation of neurogenesis | growth factor activity | positive regulation of cell development | regulation of isotype switching | regulation of adaptive immune response | negative regulation of leukocyte proliferation | regulation of RNA biosynthetic process | positive regulation of leukocyte activation | negative regulation of programmed cell death | negative regulation of heart contraction | chemical homeostasis | regulation of secretion | receptor ligand activity | immune response | cytokine activity | cell death | negative regulation of cellular protein metabolic process | regulation of cell activation | regulation of protein secretion | ion homeostasis | regulation of phosphate metabolic process | positive regulation of cytokine production | cell activation | positive regulation of protein transport | regulation of T-helper cell differentiation | negative regulation of protein metabolic process | regulation of dendrite development | regulation of cell communication | regulation of dendritic spine development | signaling | regulation of immunoglobulin production | regulation of transcription, DNA-templated | regulation of T cell proliferation | extrinsic apoptotic signaling pathway in absence of ligand | negative regulation of leukocyte apoptotic process | positive regulation of phosphorylation | regulation of cytokine production | positive regulation of regulatory T cell differentiation | regulation of nervous system development | regulation of developmental process | positive regulation of DNA metabolic process | positive regulation of immunoglobulin secretion | developmental process | negative regulation of alpha-beta T cell activation | regulation of transport | positive regulation of transcription, DNA-templated | regulation of B cell proliferation | negative regulation of cell proliferation | regulation of cell-cell adhesion | positive regulation of nucleic acid-templated transcription | cellular metal ion homeostasis | positive regulation of transcription by RNA polymerase II | positive regulation of isotype switching to IgG isotypes | positive regulation of metabolic process | positive regulation of neuron differentiation | regulation of cell projection organization | regulation of interferon-gamma production | negative regulation of lymphocyte proliferation | immune system process | regulation of protein localization | regulation of cell death | negative regulation of cell death | regulation of inflammatory response | divalent inorganic cation homeostasis | positive regulation of leukocyte cell-cell adhesion | negative regulation of cell differentiation | regulation of cellular component organization | positive regulation of signaling | signal transduction | regulation of signaling | positive regulation of gene expression | multicellular organismal process | regulation of phosphorus metabolic process
